Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Fibrogenesis in Connective Tissues

Abstract

WHILE it is now generally accepted that the cell plays a dominant part in the fibrogenesis in connective tissues, the mechanism of the formation of the fibrils of collagen and those of elastic tissue and cartilage is completely unknown. The object of this communication is to direct attention to the presence of sub-microscopical filaments in the cytoplasm of fibroblasts, osteoblasts, osteocytes and chondroblasts. The present observations were made with the electron microscope and using ultra-thin sections of tissue.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Palade, G. F., J. Exp. Med., 95, 285 (1952).

    Article  CAS  Google Scholar 

  2. Weiss, P., Arch. Entw. Mech. Org., 116, 438 (1929).

    Article  Google Scholar 

  3. Dalton, A. J., Amer. J. Anat., 89, 109 (1951). Bernard, W., Haguenau, F., Gautier, A., and Oberling, C. H., Z. Zellforsch. u. mikr. Anat., 37, 281 (1952). Sjöstrand, F. S., Nature, 171, 31 (1953). Weiss, J. M., J. Exp. Med., 98, 607 (1953).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

JACKSON, S. Fibrogenesis in Connective Tissues. Nature 173, 950–951 (1954). https://doi.org/10.1038/173950a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/173950a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing