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Chromatophore Effect of Adrenocorticotrophic Hormone

Nature volume 173, pages 35–36 (1954)Cite this article

Abstract

ADRENOCORTICOTROPHIC hormone preparations produce an effect1 similar to and even more pronounced than that of the pituitary chromatophore hormone intermedine2. When either of these hormones is injected into pale frogs, the melanophores ‘expand’ and the skin darkens. The identity of the two hormones has been assumed3 but contested4. In the frog, however, this colour change occurs not only after injection of hypophysial extracts but also after administration of choline5 and when the calcium concentration of body fluids is increased6. Investigating the chromatophore effect for the purpose of bioassay of adrenocorticotrophic hormone, we tried two preparations in fish the lipophores of which respond to intermedine but apparently not to the two other factors mentioned above7.

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References

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Author notes

  1. O. PECZENIK

    Present address: Central Laboratories, Ministry of Health, Jerusalem, Israel

Authors and Affiliations

  1. Institute of Marine Biology, Yugoslav Academy of Sciences and Arts, Rovinj, Yugoslavia

    O. PECZENIK & M. ZEI

Authors
  1. O. PECZENIK
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  2. M. ZEI
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PECZENIK, O., ZEI, M. Chromatophore Effect of Adrenocorticotrophic Hormone. Nature 173, 35–36 (1954). https://doi.org/10.1038/173035a0

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