Abstract
ABDERHALDEN1, and later Morii2, found that an injection of 2-methyl-6-amino-hydroxy (or halogen)-methylpyrimidine, which we called ‘toxopyrimidine’, in a dose of 0.12 mgm. per gm. body-weight caused attacks of convulsions and ‘running round as a ball’ of the mouse or rat fed on a certain synthetic diet.
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References
Abderhalden, Arch. Ges. Phys. (Pflüger), 240, 647 (1938).
Morii, J. Orient. Medicine, 35, 9 (1941).
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MAKINO, K., KINOSHITA, T., SASAKI, T. et al. ‘Atoxopyrimidine’. Nature 173, 34–35 (1954). https://doi.org/10.1038/173034a0
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DOI: https://doi.org/10.1038/173034a0
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