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An Antifungal Substance from a Strain of B. subtilis

Abstract

THOUGH a considerable literature has accumulated regarding the antibacterial action of B. subtilis, less attention has hitherto been paid to the antifungal action of the bacillus1. In the course of our investigation on the occurrence and isolation of antibiotic-producing micro-organisms from soil and infected foodstuff, an effort was made to collect different strains of the bacillus which would produce substances showing antifungal action especially against plant pathogenic fungi. The report of one such strain B (X) isolated from decomposed foodstuff and identified according to Bergey2 is recorded here.

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References

  1. Landy, M., Harren, G. H., Rosenham, S. B., and Colio, L. G., Proc. Soc. Exp. Biol. and Med., 67, 539 (1948). Tint, H., and Reiss, W., J. Biol. Chem., 190, 133 (1951). Walton, R. B., and Woodruff, H. B., J. Clin. Invest., 28, 924 (1949). Hobby, G. H., et al., J. Clin. Invest., 28, 927 (1949); “Ann. Rev. Biochem.”, 20, 390 (1951). Michener, H. D., and Snell, N., Arch. Biochem., 22, 208 (1949). Babad, J., et al., Nature, 170, 619 (1952).

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  2. Bergey's Manual of Determinative Bacteriology” (6th edit., 1948).

  3. Burma, D. P., J. Ind. Chem. Soc., 28, 555 (1951).

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NANDI, P., SEN, G. An Antifungal Substance from a Strain of B. subtilis . Nature 172, 871–872 (1953). https://doi.org/10.1038/172871b0

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