Abstract
GLUTATHIONE, γ-glutamylcysteinylglycine, can easily be split into glutamic acid and cysteinylglycine by mild acid hydrolysis1, and even without acid by heating in a water solution2. The tripeptide has therefore been used as material for the preparation of cysteinylglycine. In order to prepare this dipeptide for a microbiological purpose, the latter of the two methods was tried.
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References
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WIKBERG, E. Isolation of a Mixed Disulphide of Glutathione and Cysteinylglycine from a Partial Hydrolysate of Glutathione. Nature 172, 398 (1953). https://doi.org/10.1038/172398a0
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DOI: https://doi.org/10.1038/172398a0
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