Abstract
THE condensation of aromatic aldehydes with amino-acids to give coloured derivatives has had limited use in paper chromatography. Ehrlich's reagent, p-dimethyl-amino-benzaldehyde, has been used as a reagent for tryptophane and indole1 and for citrulline2. o-Phthalaldehyde has been used as a reagent for glycine, histidine and tryptophane3. Earlier workers have used other aldehydes, including vanillin, in strongly acid solution as reagents for tryptophane4.
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References
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CURZON, G., GILTROW, J. A Chromatographic Colour Reagent for a Group of Amino-Acids. Nature 172, 356–357 (1953). https://doi.org/10.1038/172356a0
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DOI: https://doi.org/10.1038/172356a0
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