Abstract
THE intraperitoneal injection of either human serum or plasma (0.5–1 ml. per 100 gm. of body-weight) inhibits urinary excretion of hyperhydrated rats. This effect disappears when either serum or plasma is dialysed against running water for 12–24 hr. Incubation at 37° C. during a period longer than eight hours destroys practically all the anti-diuretic potency of serum provided that bacterial contamination is avoided1.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Croxatto, H., Andrade, F., and Barnafi, L., Acta Physiol. Lat.-Amer., 2, 142 (1952).
Lauson, H. D., Eder, H. A., Chinard, F., Cotzias, G. C., and Greif, R., Fed. Proc., 7, 69 (1948). Lauson, H. D., Amer. J. Med., 11, 135 (1951).
Erspamer, V., Arch. Inter. Med., 90, 505 (1952).
Burn, J. H., Quart. J. Pharmacol., 4, 517 (1931).
Croxatto, H., Barnafi, L., and López, R. (in the press).
Croxatto, H., Rojas, G., and Barnafi, L., Acta Physiol. Lat.-Amer., 1, 178 (1951).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
CROXATTO, H., BARNAFI, L. Anti-Diuretic Substances of the Blood. Nature 172, 304–305 (1953). https://doi.org/10.1038/172304a0
Issue Date:
DOI: https://doi.org/10.1038/172304a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.