Abstract
ALTHOUGH transplantation of leukæmia has been secured by the intravenous inoculation of a single leukæmic cell1, transplantation of a solid tumour by a single malignant cell has not, so far as is known, been demonstrated. The fact that a leukæmic cell can normally exist as an isolated viable cell in a fluid environment is a special feature which has left open the possibility that single cells of a solid tumour may not so well survive the manipulations required for transplantation.
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References
Furth, J., and Kahn, M. C., Amer. J. Cancer, 31, 276 (1937).
Pappenheimer, A. M., J. Exp. Med., 25, 633 (1917).
Reed, J. J., and Muench, H., Amer. J. Hyg., 27, 493 (1938).
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HEWITT, H. Transplantation of Mouse Sarcoma with Small Numbers of Single Cells. Nature 170, 622–623 (1952). https://doi.org/10.1038/170622a0
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DOI: https://doi.org/10.1038/170622a0
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