Abstract
Over more than three decades, The Anthony Nolan Trust (ANT) has provided an unrelated donor (UD) for over 4000 children and adults lacking a suitable family member donor, and has remained at the forefront of developments in haematopoietic stem cell transplantation (HSCT) and bone marrow register management. These three decades have seen major changes in clinical practice of UD-HSCT, including new indications, increased use of alternative haematopoietic cell sources, significant improvement of the outcome as a result of better support care, less-toxic conditioning regimens, and better donor selection, and expansion to older patients with higher comorbidities. In order to foster our goal of improving UD-HSCT availability and outcome in a progressively more complex clinical scenario, a new initiative from ANT was launched in 2005 to convene an experts workshop to address the topical issues in this field. Four consecutive panels addressed factors influencing donor selection and transplant outcome, the use of cord blood, regulatory and accreditation issues, and future developments in this field. This report summarizes the discussions held in this workshop, which will likely develop into a periodic event where transplant clinicians, scientists and registry members will meet to share their experience and vision in the field of UD-HSCT.
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Appendix A. List of participants
Appendix A. List of participants
Jo Addada (Anthony Nolan Trust), Samia Al-Sarraj (Anthony Nolan Trust), Caroline Alvares (Royal Marsden Hospital, London), Jane Apperley (Imperial College London, Hammersmith Campus), Martín Barnado (Oxford Transplant Centre, Churchill Hospital), Finnuala Baker (Anthony Nolan Trust), Erik Bokmans (Amgen Limited, Cambridge Science Park), Linda Barber (Anthony Nolan Trust), Kay Bascombe (Anthony Nolan Trust), Joy Brennan (Royal Marsden Hospital, London), Fran Burke (Anthony Nolan Trust), Mark Caswell (Royal Liverpool Children's Hospital, Alder Hey), Richard Clark (Royal Liverpool University Hospital), Susan Cleaver (Anthony Nolan Trust), Jacqueline Cornish (Bristol Royal Hospital for Children), Steve Cox (Anthony Nolan Trust), Charles Craddock (The Queen Elisabeth Hospital, Birmingham), Anthony Dodi (Anthony Nolan Trust), Pauline Dodi (Anthony Nolan Trust), Rafael Duarte (Anthony Nolan Trust & King's College Hospital, London), Martin Ellis (Amgen Limited, Cambridge Science Park), Sandra Frater (Anthony Nolan Trust), Alex Frazier (Anthony Nolan Trust), Ian Galbraith (Glasgow Royal Infirmary), Mark Gibson (Anthony Nolan Trust), John Goldman (Anthony Nolan Trust), Ann Green (National Blood Service Bristol Centre), John Gribben (Barts and The London School of Medicine, London), Edel Harkin (Anthony Nolan Trust), Linda Hartwell (Anthony Nolan Trust), Darren Hatton (Anthony Nolan Trust), Richard Holman (Anthony Nolan Trust), Ann Hunter (Leicester Royal Infirmary), Sue Jordan (Anthony Nolan Trust), Majid Kazmi (Guy's and St Thomas’ Hospital, London), Michelle Keele (Anthony Nolan Trust), Marjorie Lawton (Anthony Nolan Trust), Effie Liakopoulou (Christie Hospital NHS Trust, Manchester), Zi Yi Lim (King's College Hospital, London), José A Limón (Imperial College London, Hammersmith Campus), Ann-Margaret Little (Anthony Nolan Trust), Tim Littlewood (The Osford Radcliffe Hospital), Stephen Mackinnon (Royal Free and University College Medical School, London), Alejandro Madrigal (Anthony Nolan Trust), David Marks (United Bristol Healthcare Trust), Stephen Marsh (Anthony Nolan Trust), Daniel McCloskey (Barts and The London School of Medicine), Katie Matthews (Anthony Nolan Trust), Neema Mayor (Anthony Nolan Trust), Stephen McEwan (Anthony Nolan Trust), Ghulam Mufti (King's College Hospital, London), Lucy Nicholls (United Bristol Healthcare Trust), Sandra Novack (Anthony Nolan Trust), Eduardo Olavarria (Imperial College London, Hammersmith Campus), Kim Orchard (Southampton General Hospital), Antonio Pagliuca (King's College Hospital, London), Derwood Pamphilon (Bristol Royal Hospital for Children), Anne Parker (Glasgow Royal Infirmary), Fotini Paterniou (Anthony Nolan Trust), (Anthony Nolan Trust), Andy Peniket (The Oxford Radcliffe Hospital), Jackie Penny (Amgen Limited, Cambridge Science Park), Mike Potter (Royal Marsden Hospital, London), Kay Poulton (Manchester Royal Infirmary), Ray Powles (Parkside Oncology Clinic, London), Chrissy Roberts (Anthony Nolan Trust), Nigel Russell (Nottingham City Hospital NHS Trust), Diane Samson (Imperial College London, Hammersmith Campus), Anila Shah (Anthony Nolan Trust), Anne Shurlock (Anthony Nolan Trust), Bronwen Shaw (Nottingham City Hospital NHS Trust), Rod Skinner (Royal Victoria Infirmary, Newcastle Upon Tyne), Mary Slatter (Newcastle General Hospital), David Tate (Manchester Royal Infirmary), Franco Tavarozzi (Anthony Nolan Trust), Caroline Thornton (Anthony Nolan Trust), Paul Travers (Anthony Nolan Trust), Paul Veys (Great Ormond Street Hospital, London), Robert Wynn (Royal Manchester Children's Hospital), John Yin (Manchester Royal Infirmary).
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Duarte, R., Pamphilon, D., Cornish, J. et al. Topical issues in unrelated donor haematopoietic stem cell transplants: a report from a workshop convened by the Anthony Nolan Trust in London – 2005. Bone Marrow Transplant 37, 901–908 (2006). https://doi.org/10.1038/sj.bmt.1705365
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DOI: https://doi.org/10.1038/sj.bmt.1705365