Abstract
STERIC effects may be either thermodynamic or kinetic, that is, they may influence either reaction equilibria or reaction rates: this note is concerned with kinetic steric effects. Such effects depend on mechanism, and even the sign of a kinetic steric effect can be altered by a change of mechanism. ‘Steric hindrance’, obviously an inadequate title under which to summarize thermodynamic steric effects, thus becomes inadequate even to cover all kinetic steric effects.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Dostrovsky, Hughes and Ingold, J. Chem. Soc., 173 (1946).
(a) Hughes, J. Chem. Soc., 255 (1935). Cooper, Hughes, Ingold and MacNulty, ibid., 1183, 1280, 1283 (1937).(b) Hughes, Ingold, Martin and Meigh, Nature, 166, 679 (1950), and unpublished results. (c) Shorter and Hinshelwood, J. Chem. Soc., 2412 (1949). (d) Brown and Fletcher, J. Amer. Chem. Soc., 71, 1845 (1949).
(a) Results of present authors. (b) Prof. P. D. Bartlett and co-workers reported similarly large factors at an International Colloquium in Montpellier, France (April 1950), where our results and conclusions were also communicated.
Dostrovsky and Hughes, J. Chem. Soc., 171 (1946).
Hughes and Ingold, J. Chem. Soc., 2038, et seq. (1948). cf. Whitmore and Stahly, J. Amer. Chem. Soc., 55, 4153 (1933).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BROWN, F., DAVIES, T., DOSTROVSKY, I. et al. Steric Retardation and Steric Acceleration. Nature 167, 987–988 (1951). https://doi.org/10.1038/167987a0
Issue Date:
DOI: https://doi.org/10.1038/167987a0
This article is cited by
-
Das Prinzip der Äthylogie in der organischen Chemie
Experientia (1957)
-
Quantitative investigation of steric hindrance
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science (1956)
-
Wagner Changes, Synartetic Acceleration and Synartetic Ions
Nature (1951)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
