Abstract
It has been shown that ethyl carbamate, which inhibits the tyrosine – tyrosinase reaction, accelerates the autoxidation of 3,4-dihydroxyphenylalanine to melanin1. Other substances known to inhibit the tyrosine – tyrosinase reaction have been investigated for this accelerating effect. One such substance is hydroquinone mono-benzyl ether2,3. The inhibition of the tyrosine – tyrosinase reaction by hydroquinone mono-benzyl ether was confirmed, but no evidence of any accelerating effect on the autoxidation of 3,4-dihydroxyphenylalanine was obtained; in fact, there was a small but definite degree of inhibition of this reaction.
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LEA, A. Effect of Hydroquinone Mono-Benzyl Ether on Melanin Formation in vitro. Nature 167, 906 (1951). https://doi.org/10.1038/167906a0
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DOI: https://doi.org/10.1038/167906a0
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