Abstract
THE regulation of energy intake both in the growing and in the adult animal is one of the most important physiological regulations. The essential characteristics of this regulation in the adult, its precision, sensitivity and accuracy, the individual and strain differences, the differences due to environmental factors (essentially temperature) as well as the alterations in metabolism and body composition correlated with these changes in food intake, have been studied by A. Mayer and his collaborators1. The importance of the integrity of the hypothalamic region of the brain as well as the hyperphagia and resulting obesity due to the hypothalamic lesion have been studied by J. Brobeck and reviewed by him2.
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References
Gasnier, A., and Mayer, A., Ann. Physiol. et Physicochim. Biol., 15, 146, 157, 186, 195 and 210 (1939). Chevillard, L., and Mayer, A., ibid., 15, 271 (1939). Chevillard, L., Gasnier, A., and Mayer, A., ibid., 15, 282, 294 and 305 (1939).
Brobeck, J. R., Physiol. Rev., 26, 541 (1946).
Ingle, D. J., Proc. Soc. Exp. Biol. and Med., 72, 604 (1949).
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MAYER, J., VITALE, J. & BATES, M. Mechanism of the Regulation of Food Intake. Nature 167, 562–563 (1951). https://doi.org/10.1038/167562a0
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DOI: https://doi.org/10.1038/167562a0
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