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A Possible Structure for Codecarboxylase

Nature volume 167, pages 556–557 (1951)Cite this article

Abstract

THE thermostable factor which functions in the enzymatic decarboxylation of a number of amino-acids is known as codecarboxylase. Its recognition as a phosphorylated derivative of pyridoxal was confirmed by the preparation of a highly active material through direct phosphorylation of pyridoxal with phosphoryl chloride1. Elementary analysis of the synthetic product indicated the presence of one phosphate group in the molecule; but the exact location of this group was uncertain.

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Author information

Authors and Affiliations

  1. Lister Institute of Preventive Medicine, London, S.W.1

    J. BADDILEY & E. M. THAIN

  2. Medical Research Council Unit for Chemical Microbiology, Department of Biochemistry, University, Cambridge,

    A. W. RODWELL

Authors
  1. J. BADDILEY
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  2. E. M. THAIN
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  3. A. W. RODWELL
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BADDILEY, J., THAIN, E. & RODWELL, A. A Possible Structure for Codecarboxylase. Nature 167, 556–557 (1951). https://doi.org/10.1038/167556b0

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