Abstract
ZINC is known to be a component of carbonic anhydrase1 and is thought to be part of uricase2. It also is a non-specific divalent activator of several other enzymes. The striking effect of zinc deficiency on organic acid formation by fungi (‘zinc shunt’) has recently been reviewed3. Some older evidence in the literature and a generalized interpretation given for the zinc effect made it possible to predict4 that similar effects would be obtained with deficiencies of other nutrient elements. This has been confirmed5.
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References
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Baldwin, E. “Dynamic Aspects of Biochemistry” (Macmillan, New York, 1947).
Foster, J. W., “Chemical Activities of Fungi” (Academic Press, New York, 1949).
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Chesters, C. G. C., and Robinson, G. N., Nature, 165, 851 (1950).
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Foster, J. W., and Davis, J. B., Arch. Biochem., 21, 135 (1949).
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FOSTER, J., DENISON, F. Role of Zinc in Metabolism. Nature 166, 833–834 (1950). https://doi.org/10.1038/166833a0
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DOI: https://doi.org/10.1038/166833a0
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