Abstract
IN 1948, Prof. G. Häggqvist1 reported the production of tetraploid frogs (Rana temporaria) by colchicine treatment at fertilization, all previous workers having been unsuccessful. Chromosome counts were not made. Instead, tetraploidy was inferred from the relatively greater volume of epidermal nuclei of some treated animals as compared with controls (ratio 1 : 1.87, the theoretical ratio for tetraploidy being 1 : 2.00).
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References
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BEATTY, R., FISCHBERG, M. “Polyploidy in Rabbits”. Nature 166, 238–239 (1950). https://doi.org/10.1038/166238a0
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DOI: https://doi.org/10.1038/166238a0
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