Abstract
FROM a large number of investigations it is known that the appearance of the symptoms of polyneuritis in animals fed on an aneurin-deficient diet is accelerated by increasing the amounts of carbohydrate fed and delayed by replacing carbohydrate by fat1. This has led to the formulation of the so-called ‘sparing action of fat on vitamin B1’ 2.
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References
See Westenbrink, H. G. K., Arch. Néerl. de Physiol., 19, 94 (1934). Williams, R. R., and Spies, T. D., “Vitamin B1 ”, 266 (New York, 1939).
Evans, H. M., and Lepkovsky, S., J. Biol. Chem., 83, 269 (1929).
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Kemmerer, A. R., and Steenbock, H., J. Biol. Chem., 103, 353 (1933).
Westenbrink, H. G. K., Arch. Néerl. de Physiol., 19, 116 (1934).
Evans, H. M., and Lepkovsky, S., J. Biol. Chem., 108, 439 (1935).
Westenbrink, H. G. K., and Steyn Parvé, Elizabeth P., Z. Vitaminforsch., 21, 461 (1950).
Fisher, R. A., “Statistical Methods for Research Workers” (London, 1948).
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GRUBER, M. Nature of the Vitamin B1-sparing Action of Fat. Nature 166, 78 (1950). https://doi.org/10.1038/166078a0
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DOI: https://doi.org/10.1038/166078a0
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