Abstract
DUSTIN1, acting on a suggestion made by Schütz, investigated the action of sodium cyanate on cells in mitosis. He reported that six hours after a dose of 5 mgm. had been given to mice, it was possible to see pycnotic degeneration in cells of the intestinal mucosa, splenic lymphoid tissue and cortical tissue of the thymus. Loveless and Revell2 considered that these effects were due to the general toxicity of the cyanate ion and not to a specific anti-mitotic action.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Dustin, P., Nature, 159, 794 (1947).
Loveless, A., and Revell, S., Nature, 164, 938 (1949).
Bader, R., Dupré, D. J., and Schütz, F., Biochim. Biophys. Acta, 2, 543 (1948).
Campbell, A. C. P., J. Path. Bact., 60, 633 (1948).
Schütz, F., Experientia, 5, 133 (1949).
Skipper, H. E., Bryan, C. E., Riser, W. H., jun., Welty, M., and Stelzenmuller, A., J. Nat. Cancer Inst., 9, 77 (1948).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
DEAN, R., GUNZ, F. Action of Cyanate on the Bone Marrow of Rats. Nature 165, 895–896 (1950). https://doi.org/10.1038/165895b0
Issue Date:
DOI: https://doi.org/10.1038/165895b0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
