Abstract
THE crystalline material described above has been tested against several organisms used chiefly for microbiological assay. These tests have shown that the crystals are markedly toxic to the organism Leuconostoc mesenteroides P-60 at a concentration as low as 5 pgm. per ml. of liquid medium, the cells being agglutinated and acid production substantially reduced. With higher concentrations, of 50 μgm. per ml. or more, growth and acid-production are almost entirely suppressed. For this organism the limit for detecting a toxic effect is about 1–2 μgm. per ml. of medium. The following figures, observed after 16 hr. incubation on a full-growth medium at 37°, serve to illustrate the sensitivity of Leuconostoc mesenteroides P-60.
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HEATHCOTE, J. Toxic Effect of the Crystals from ‘Agenized’ Zein on Certain Acid-producing Bacteria. Nature 164, 439 (1949). https://doi.org/10.1038/164439a0
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DOI: https://doi.org/10.1038/164439a0
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