Abstract
BENZIMIDAZOLES have been prepared by oxidation of a mixture of an o-phenylene diamine and an aldehyde with cupric salts1 (for example, cupric acetate), and it has been pointed out2 that the reaction proceeds by the oxidative ring closure of the mono-Schiff's bases first obtained:
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References
Weidenhagen, Ber., 69, 2263 (1936).
Weidenhagen and Weedon, Ber., 71, 2347 (1938).
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STEPHENS, F. Heterocyclic Compounds from Schiff's Bases. Nature 164, 243 (1949). https://doi.org/10.1038/164243a0
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DOI: https://doi.org/10.1038/164243a0
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