Abstract
WE have described elsewhere a technique for the production of experimental macrocytic anæmia in the rat by the formation of a cul-de-sac in the small intestine, and preliminary observations suggested that a hæmatological remission could be induced in some of the anæmic animals by treatment with purified liver extracts1,2. An experiment was planned to test the effects of continued treatment with large doses of purified liver extract ('Anahæmin'), pteroyl glutamic acid and vitamin B12 on this experimental anæmia, and the results so far are sufficiently interesting to warrant this brief report.
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Watson, G. M., Cameron, D. G., and Witts, L. J., Lancet, 2, 404 (1948).
Cameron, D. G., Watson, G. M., and Witts, L. J., Blood (in the press).
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CAMERON, D., CALLENDER, S., WATSON, G. et al. Experimental Macrocytic Anæmia in the Rat Treated with Purified Liver Extract, Pteroyl Glutamic Acid and Vitamin B12. Nature 164, 188 (1949). https://doi.org/10.1038/164188a0
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DOI: https://doi.org/10.1038/164188a0
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