Abstract
THE catalysis of oxalacetate decarboxylation by metallic ions constitutes a simple 'model' system, the properties of which may throw some light on the biological decarboxylation mechanisms. Kornberg, Ochoa and Mehler1 have described the formation of an unstable complex between oxalacetate and aluminium ions, which possesses a characteristic ultra-violet absorption spectrum. Recent studies from this laboratory2 have shown that iron and copper differ in many respects as regards their ability to accelerate the decomposition of oxalacetate.
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References
Kornberg, A., Ochoa, S., and Mehler, A. H., J. Biol. Chem., 174, 159 (1948).
Nossal, P. M., Austral. J. Exp. Biol. (in the press).
Nossal, P. M., Austral. J. Exp. Biol., 26, 531 (1948).
Nossal, P. M., Nature 162, 36 (1948).
Nossal, P. M., and Kerr, D. I. B., Austral. J. Exp. Biol., 26, 553 (1948).
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NOSSAL, P. Oxalacetate Decarboxylation by Iron and Copper. Nature 163, 405 (1949). https://doi.org/10.1038/163405a0
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DOI: https://doi.org/10.1038/163405a0
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