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Photo-electric Counting of Individual Microscopic Plant and Animal Cells

Abstract

A PHOTO-ELECTRIC apparatus for counting individual microscopic cells in fluid suspension has been constructed in this laboratory. A sufficiently large signal-to-noise ratio from a single cell or a part of it has been obtained by the use of a specially designed dark-field system and an RCA 931-A multiplier phototube. The phototube is followed by an amplifier which operates a mechanical counter. As it was not possible to arrange the cells in one line in a capillary space, a scanning method using an ordinary counting chamber was evolved.

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LAGERCRANTZ, C. Photo-electric Counting of Individual Microscopic Plant and Animal Cells. Nature 161, 25–26 (1948). https://doi.org/10.1038/161025b0

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