Abstract
A Special modification of adsorption chromatography on charcoal has been shown by Tiselius1 to be a useful and selective method of analysis for mixtures containing closely related substances. The method was originally designed for the investigation of breakdown products of proteins, though it has not yet been extensively applied to relatively high-molecular polypeptides, since these are often such complex mixtures as to render any type of analysis extremely difficult.
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References
Tiselius, A., "Advances in Protein Chemistry", 3, 67 (1947), with references to earlier work.
Sanger, F., Nature, 160, 295 (1947).
Sanger, F., Biochem., 39, 507 (1945).
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TISELIUS, A., SANGER, F. Adsorption Analysis of Oxidized Insulin. Nature 160, 433–434 (1947). https://doi.org/10.1038/160433b0
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DOI: https://doi.org/10.1038/160433b0
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