Abstract
DURING an investigation on the variation of the chromosome system in human cancer of the uterus, we were able to observe frequently (in six epitheliomas of the uterus portio) a mitotic figure with a peculiar aspect of the chromosomes. In such cell divisions (which appear mixed with normal, heteroploid and polyploid ones) 24 chromosomes are present. Their shape resembles the meiotic one, being strongly contracted. The prophase shows thick threads, as in the pachytene stage, and later the synaptic males appear unsplit. No chiasmata are to be seen; the metaphase shows that every element is double.
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BARIGOZZI, C., CUSMANO, L. Chromosome Numbers in Cancer Cells. Nature 159, 505–506 (1947). https://doi.org/10.1038/159505b0
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DOI: https://doi.org/10.1038/159505b0
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