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Effect of Mono- and Divalent Salts on Red Blood Cells

Abstract

Greville and Lehmann1 reported that less hæmolysis occurred when human blood was stored with M/7 magnesium chloride as an anticoagulant than if isotonic sodium citrate was used. We have investigated this phenomenon for several reasons, one of which was its possible practical bearing on the storage of sheep blood corpuscles used for the Wassermann reaction in the diagnosis of syphilis.

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References

  1. Greville, G. D., and Lehmann, H., J. Physiol., 103, 175 (1943).

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  2. Aub, J. C., Fairhall, L. T., Minot, A. S., and Reznikoff, P., "Medicine Monographs, Lead Poisoning, VII" (Williams and Wilkins Company, Baltimore, 1926).

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  3. Dyson, M., Plaut, G., and Vaughan, J., Quart. J. Physiol., 32, 255 (1944).

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  4. Walters, J. H., Rossiter, R. J., and Lehmann, H., "The Marasmus Syndrome, Study of 2000 cases chiefly Indian Prisoners of War Repatriated from Japanese Prison Camps" (General Headquarters, India Command, 1946).

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LEHMANN, H., LAWS, J. & AHMED, N. Effect of Mono- and Divalent Salts on Red Blood Cells. Nature 159, 169–170 (1947). https://doi.org/10.1038/159169b0

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