Abstract
THE demonstration that purified and apparently homogeneous specimens of ‘A-substance’ prepared from commercial hog gastric mucin possess both A and O blood-group specificity, whereas A-substance isolated from the fluid contents of human pseudomucinous ovarian cysts1 shows no significant O activity, suggested that a closer and more detailed examination of the hog mucin “A-substance” for homogeneity should be undertaken. The best specimens of A-substance of animal origin examined so far have been obtained from commercial preparations of hog gastric mucin or pepsin2, each batch of which contains material from the stomachs of many hogs. In view of the differences known to exist in the serological specificity of the gastric secretions of man3, it seems not improbable that similar serological differences exist in the mucin preparations derived from individual hog's stomachs, and an examination of the serological properties of the mucoids isolated from single stomachs was therefore undertaken.
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AMINOFF, D., MORGAN, W. & WATKINS, W. Specific Serological Characters of the Mucoids of Hog Gastric Mucin. Nature 158, 879 (1946). https://doi.org/10.1038/158879a0
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DOI: https://doi.org/10.1038/158879a0
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