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Measurement of the Photodynamic Effect of Cancerogenic Substances with Biological Indicators

Abstract

THE photodynamic effect of cancerogenic substances was examined by Mottram and Doniach1 using Paramecium. They found that the cancerogenic substances had a stronger effect than the non-cancerogenic photosensitizers. We have tried to estimate the photodynamic effect of cancerogenic substances by means of a standard biological indicator, namely, the 3rd stage larvæ of Drosophila melanogaster, as it is known that they are suitable for the standardizing and measuring of radiation.

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  1. Mottram and Doniach, Nature, 140, 933 (1937).

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MATOLTSY, G., FÁBIÁN, G. Measurement of the Photodynamic Effect of Cancerogenic Substances with Biological Indicators. Nature 158, 877–878 (1946). https://doi.org/10.1038/158877b0

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