Abstract
Two enzyme systems catalysing the transamination of amino-acids have been prepared from muscle and heart tissue and described by one of us (M.K.)1,2. These enzymes were termed glutamic aminopherase and aspartic aminopherase, according to their specific primary substrates3. The latter is easily inactivated in the initial stages of purification (dialysis, etc.), and can be reactivated by a thermostable coenzyme present in boiled tissue extracts4; while the former can be prepared from muscle tissue without loss of activity.
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Lènard, P., and Straub, F. B., Studies Inst. Med. Chem., Univ. Szeged, 2, 59 (1942).
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KRITZMANN, M., SAMARINA, O. Reversible Splitting of Glutamic Aminopherase. Nature 158, 104 (1946). https://doi.org/10.1038/158104a0
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DOI: https://doi.org/10.1038/158104a0
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