Abstract
THE monograph on the proteins of blood serum by Kai O. Pedersen*, from Prof. Svedberg's laboratory at Uppsala, brings home forcibly the present complexity of the subject. Although any one of the usual methods of analysis gives apparently clear-cut fractions, each fraction when analysed by some other method usually turns out to be a mixture. The obvious remedy, to fractionate by each method in turn, is impracticable because some of the analytical methods are difficult to use in a preparative way. After a heroic attempt to achieve a complete separation, chiefly by means of ammonium sulphate with ultracentrifugal analysis, Dr. Pedersen had to confess defeat.
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PHILPOT, J. Serum Proteins in the Ultracentrifuge. Nature 156, 247 (1945). https://doi.org/10.1038/156247b0
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DOI: https://doi.org/10.1038/156247b0