Abstract
DURING the past fifty or sixty years, attempts to reconcile the massive accumulation of iron in various cells and tissues in the body with altered hæmoglobin has led to the universal adoption of the terms 'hæmo-siderosis' and 'hæmochromatosis'. This terminology has focused attention on the metabolism of hæmoglobin and its derivatives, to the exclusion of the consideration of other potential sources of this iron pigment. However, in hæmochromatosis, almost all investigators are agreed that there is no evidence of increased blood destruction to account for the intracellular iron pigment.
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GILLMAN, T., GILLMAN, J. Mitochondrial Origin of Cytosiderin (Iron Pigment) in the Liver of Human Pellagrins. Nature 154, 148 (1944). https://doi.org/10.1038/154148a0
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DOI: https://doi.org/10.1038/154148a0
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