Abstract
IDIOPATHIC porphyria is especially interesting as the urinary pigment uroporphyrin III associated with this disease resembles closely in its chemical structure the protoporphyrin of hæmoglobin. Urinary uroporphyrin may provide here an index of the rate of protoporphyrin formation in the body, and it seemed important to obtain information on this point, and to observe if uroporphyrin III excretion is augmented by administration of substances which, on a theoretical basis at least, could function as protoporphyrin precursors.
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References
Kawabe, K., J. Biochem., 20, 243 (1934).
Waldenström, J., and Vahlquist, B., Z. Physiol Chem., 260, 189 (1939).
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KENCH, J. Porphyrin Metabolism in Idiopathic Porphyria. Nature 154, 117–118 (1944). https://doi.org/10.1038/154117a0
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DOI: https://doi.org/10.1038/154117a0
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