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Role of Manganese in the Biological Synthesis of Ascorbic Acid

Abstract

I HAVE adduced evidence1 that manganese has a specific role in the synthesis of ascorbic acid by plants and animals. Until now the evidence of the synthesis of ascorbic acid in presence of manganese has been chemical; that is, by titration with the indophenol reagent. Evidence that the indophenol-reducing substance synthesized is identical with vitamin C has now been obtained.

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  1. NATURE, 141, 203; 143, 811; 144, 868; 151, 641. Biochem. Z., 301, 238. Oesterr. Chem. Z., 42, 315. J. Indian. Chem. Soc., 17, 705. Ann. Biochem. Exp. Med., 2, 9.

  2. Biochem. J., 25, 888.

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RUDRA, M. Role of Manganese in the Biological Synthesis of Ascorbic Acid. Nature 153, 743–744 (1944). https://doi.org/10.1038/153743b0

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