Abstract
RECENT investigations on protein metabolism and nutrition have increasingly emphasized the importance of individual amino-acid deficiencies in producing specific clinical states and pathological appearances1. It has been shown2 that fatty livers can be produced in rats by dietary control. This latter work, and the findings of Miller and Whipple3 that methionine could protect the liver against damage by chloroform, suggested to us that the present epidemic of infective hepatitis and the increased incidence of 'post-arsphenamine' jaundice might in some measure be conditioned by a sub-optimal protein intake leading to a latent methionine deficiency.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Dixon, T. F., NATURE, 153, 289 (1944).
Best, C. H., and Lucas, C. C., "Choline Chemistry and Significance as a Dietary Factor", "Vitamins and Hormones", 1 (1943).
Miller, L. L., and Whipple, G. H., J. Exp. Med., 76, 421 (1942).
Himsworth, H. P., and Glynn, L. E., Lancet, i, 457 (1944).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BEATTIE, J., MARSHALL, J. Methionine in the Treatment of Liver Damage. Nature 153, 525–526 (1944). https://doi.org/10.1038/153525b0
Issue Date:
DOI: https://doi.org/10.1038/153525b0
This article is cited by
-
Sulphur-containing Amino-Acids and Jaundice
Nature (1944)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
