Abstract
THE issue of the British Medical Journal dated April 15 includes eight papers which record the results of work done at one of the four main centres established in March 1943 by the Penicillin Clinical Trials Committee of the Medical Research Council. A leading article comments on these papers and on other work in the United States, where much larger supplies of penicillin are available, so that work on a larger scale is possible. In the first article, Prof. L. P. Garrod and Dr. Christie describe the work and policy of the centre at which all this work was done. Other articles deal with the systemic administration of penicillin by continuous intravenous drip, intramuscular injection, drip transfusion into the bone marrow of the sternum and continuous intramuscular drip transfusion; with the effects of penicillin on infections of the mandible and of bone, the latter indicating that treatment of chronic bone infections is not yet satisfactory; with its use as a local application to lesions of soft tissues (wounds, abscesses, cellulitis and infected skin eruptions); and its effects on breast abscess and certain skin diseases.
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Clinical Use of Penicillin. Nature 153, 521 (1944). https://doi.org/10.1038/153521a0
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DOI: https://doi.org/10.1038/153521a0