Abstract
MANY attempts have been made to demonstrate a possible endocrine influence of the uterus upon the ovaries of animals. The most recent report dealing with this subject1 describes degenerative changes in the ovaries of hysterectomized rabbits. An extract of rabbit endometrium appeared to retard the process of ovarian atrophy in another group of hysterectomized rabbits. The authors suggest that a protective influence upon the ovary is exerted by the uterus. Some clinical reports support the observation that conservation of some endometrium at the time of hysterectomy in the human lessens the severity of the menopausal syndrome following such an operation2. Other investigators leave the subject an open question.
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Mishell, D. R., and Molytoff, L., Endocrinology, 28, 436 (1941).
Marx, R., Catchpole, H. R., and McKennon, B. J., Surg. Gynec. and Obstet., 63, 170 (1936).
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PALMER, A., FULTON, L. Decreased Ovarian Response to Chorionic Gonadotropin following Hysterectomy in the Mouse. Nature 148, 596 (1941). https://doi.org/10.1038/148596a0
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DOI: https://doi.org/10.1038/148596a0
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