Abstract
IT has recently been observed1 that the carrier weights, that is, the weight of protein carrying one gram–equivalent of prosthetic group, of a class of conjugated proteins, the chromoproteins, is in many cases equal to the Svedberg unit of about 17,600 gm. In no case is it appreciably less. Data for various conjugated proteins have since become available, and are shown along with the previous data in the accompanying tables. References for the latter data are given in the previous paper1. The carrier weights given include the weights of the prosthetic groups, and are therefore too high. The latter are, however, mostly unknown, but as they are certainly comparatively small (4 per cent in haemoglobin, 1 per cent in the flavins) this error is not serious; moreover, the same systematic error is incurred in calculating the Svedberg unit from ultracentrifugal molecular weight determinations.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Broda, E. E., Goodeve, C. F., and Lythgoe, R. J., J. Physiol., 98, 397 (1940).
Keilin, D., and Mann, T., NATURE, 143, 23 (1939).
Keilin, D., and Mann, T., Biochem. J., 34, 1163 (1940).
Green, D. E., "The Mechanism of Biological Oxidations" (Cambridge, 1940), p. 124.
Pedersen, K. O., and Heidelberger M., J. Gen. Physiol., 19, 95 (1935).
Dalton, H. R., and Nelson, J. M., J. Amer. Chem. Soc., 61, 2469 (1939).
cf. Kubowitz, F., Biochem. Z., 299, 51 (1938).
Lovell-Janison, P. L., and Nelson, J. M., J. Amer. Chem. Soc., 62, 1409 (1940).
Straub, F. B., Biochem. J., 33, 787 (1939).
Corran, H. S., Dewan, J. G., Gordon, A. H., and Green, D. E., Biochem. J., 33, 1694 (1939).
Philpot, J. St. L., Biochem. J., 33, 1707 (1939).
Sumner, J. B., and Dounce, A. L., J. Biol. Chem., 127, 439 (1939).
cf. Svedberg, Th., and Pedersen, K. O., "The Ultracentrifuge". Oxford University Press (1940).
See "containing weights", Cohn, E. J., Physiol. Rev., 5, 349 (1925).
Warburg, O., and Christian, W., Biochem. Z., 298, 150 (1938).
Negelein, E., and Brömel, H., Biochem. Z., 300, 225 (1939).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BRODA, E., GOODEVE, C. CARRIER WEIGHTS OF CONJUGATED PROTEINS. Nature 148, 200–201 (1941). https://doi.org/10.1038/148200a0
Issue Date:
DOI: https://doi.org/10.1038/148200a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.