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CARRIER WEIGHTS OF CONJUGATED PROTEINS

Abstract

IT has recently been observed1 that the carrier weights, that is, the weight of protein carrying one gram–equivalent of prosthetic group, of a class of conjugated proteins, the chromoproteins, is in many cases equal to the Svedberg unit of about 17,600 gm. In no case is it appreciably less. Data for various conjugated proteins have since become available, and are shown along with the previous data in the accompanying tables. References for the latter data are given in the previous paper1. The carrier weights given include the weights of the prosthetic groups, and are therefore too high. The latter are, however, mostly unknown, but as they are certainly comparatively small (4 per cent in haemoglobin, 1 per cent in the flavins) this error is not serious; moreover, the same systematic error is incurred in calculating the Svedberg unit from ultracentrifugal molecular weight determinations.

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References

  1. Broda, E. E., Goodeve, C. F., and Lythgoe, R. J., J. Physiol., 98, 397 (1940).

    Article  CAS  Google Scholar 

  2. Keilin, D., and Mann, T., NATURE, 143, 23 (1939).

    Article  ADS  CAS  Google Scholar 

  3. Keilin, D., and Mann, T., Biochem. J., 34, 1163 (1940).

    Article  CAS  Google Scholar 

  4. Green, D. E., "The Mechanism of Biological Oxidations" (Cambridge, 1940), p. 124.

    Google Scholar 

  5. Pedersen, K. O., and Heidelberger M., J. Gen. Physiol., 19, 95 (1935).

    Article  Google Scholar 

  6. Dalton, H. R., and Nelson, J. M., J. Amer. Chem. Soc., 61, 2469 (1939).

    Article  Google Scholar 

  7. cf. Kubowitz, F., Biochem. Z., 299, 51 (1938).

    Google Scholar 

  8. Lovell-Janison, P. L., and Nelson, J. M., J. Amer. Chem. Soc., 62, 1409 (1940).

    Article  Google Scholar 

  9. Straub, F. B., Biochem. J., 33, 787 (1939).

    Article  CAS  Google Scholar 

  10. Corran, H. S., Dewan, J. G., Gordon, A. H., and Green, D. E., Biochem. J., 33, 1694 (1939).

    Article  CAS  Google Scholar 

  11. Philpot, J. St. L., Biochem. J., 33, 1707 (1939).

    Article  CAS  Google Scholar 

  12. Sumner, J. B., and Dounce, A. L., J. Biol. Chem., 127, 439 (1939).

    CAS  Google Scholar 

  13. cf. Svedberg, Th., and Pedersen, K. O., "The Ultracentrifuge". Oxford University Press (1940).

    Google Scholar 

  14. See "containing weights", Cohn, E. J., Physiol. Rev., 5, 349 (1925).

    Google Scholar 

  15. Warburg, O., and Christian, W., Biochem. Z., 298, 150 (1938).

    CAS  Google Scholar 

  16. Negelein, E., and Brömel, H., Biochem. Z., 300, 225 (1939).

    CAS  Google Scholar 

Download references

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BRODA, E., GOODEVE, C. CARRIER WEIGHTS OF CONJUGATED PROTEINS. Nature 148, 200–201 (1941). https://doi.org/10.1038/148200a0

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