Abstract
IT is well known that germicides depress the respiration of both the micro-organisms and the tissues with which they come in contact. It has been shown that the depressant actions of a germicide on the respiration of the micro-organism and of the host tissue are directly correlated with the toxicities of the germicide for the organism and the host, and a comparison of these respiratory effects by manometric methods has been proposed for the evaluation of germicides1.
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Butaben, Merck . We wish to thank Dr. R. T. Major of Merck and Co., Inc., for a gift of this material.
Trowell, O. A., and Willmer, E. N., J. Exptl. Biol., 16, 60 (1939); Pomerat, C. M., and Willmer, E. N., ibid., 16, 232 (1939).
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COOK, E., KREKE, C. Ability of Respiratory-Stimulating Factors to Overcome Toxic Action of Germicides on Moulds. Nature 146, 688 (1940). https://doi.org/10.1038/146688a0
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DOI: https://doi.org/10.1038/146688a0
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