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The Initial Stages of Glycolysis in Muscle Extracts

Abstract

WE have already made a preliminary report1 on the preparation from rabbit muscle, by a method involving repeated extraction with phosphate solution, of solutions of the glycolytic enzyme system, which appear to be more free from associated co-enzymes than are extracts prepared by other methods. The extracts convert starch to lactic acid in the presence of muscle Kochsaft, but do not do so in the presence of adenosine triphosphate, magnesiumions, cozymase and a trace of hexose diphosphate ; an account of their properties, with the evidence of a participation of a new co-enzyme, will shortly be given in detail elsewhere.

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References

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KENDAL, L., STICKLAND, L. The Initial Stages of Glycolysis in Muscle Extracts. Nature 140, 360–361 (1937). https://doi.org/10.1038/140360b0

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