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Glycogen In Cartilage

Nature volume 130, pages 996–997 (1932)Cite this article

Abstract

IN 1923 Robison1 showed that when bones of rachitic rats were immersed in solutions of calcium hexose-monophosphate or glycerophosphate, a dense deposit of calcium was formed in the matrix of the hypertrophic cartilage at the site where calcium would have occurred in vivo if the rats had been fed on a normal diet. He showed that the deposition of soluble calcium salts as an insoluble phosphate of calcium was due to the activity of an enzyme, phosphatase, which he was able to separate from bone. Fell grew the isolated femora of six-day chick embryos in vitro and with Robison2 proved that the enzyme is formed by or in the hypertrophic cells of the cartilage.

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Authors and Affiliations

  1. Department of Anatomy, University College, London

    H. A. HARRIS

Authors
  1. H. A. HARRIS
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HARRIS, H. Glycogen In Cartilage. Nature 130, 996–997 (1932). https://doi.org/10.1038/130996a0

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