Abstract
INVESTIGATION of the utilisation by the body of various compounds related to the sugars may be expected to throw light upon the intermediary metabolism of the carbohydrates and is, at any rate, of scientific interest. In this connexion, dihydroxy-acetone, methylglyoxal, and glyceric aldehyde may be cited. Although the former antidotes insulin hypoglycæmia in both man and animals, yet, administered by mouth to human beings on a fasting stomach, it itself produces a definite hypoglyæmia (E. P. Cathcart and J. Markowitz: Biochem. Jour., vol. 21, p. 1419; 1927). The fall may be compared with the secondary decrease in the blood-sugar after the ingestion of glucose, and may be due to stimulation of secretion of insulin from the pancreas. At the same time, the increased tension of carbohydrate in the liver may arrest the processes of glyconeogenesis and glycogenolysis.
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Aspects of Carbohydrate Metabolism.: II. Nature 126, 740–741 (1930). https://doi.org/10.1038/126740a0
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DOI: https://doi.org/10.1038/126740a0