Abstract
I HAVE very little doubt that Dr. Gorter is right in suspecting that the method which is commonly used for determining the volume of the red blood corpuscles by centrifugalisation is not trustworthy (NATURE, June 23, p. 845). Whether the red corpuscles are biconcave discs or hollowed cones, or indeed, whatever their shape may be, they cannot be packed together without leaving spaces between them unless they are deformed: and if they are deformed there is every reason to be suspicious about their water content remaining unaltered.
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BOYCOTT, A. The Concentration of Hæmoglobin in Blood Corpuscles. Nature 112, 164 (1923). https://doi.org/10.1038/112164b0
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DOI: https://doi.org/10.1038/112164b0
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