Nature Index |
Featured
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Nature Index |
Four change-makers seek impact in medical research
Bringing fresh perspectives to long-standing health challenges, these scientists are using techniques such as big-data analytics and AI to push the field.
- Amy Coombs
- & Sandy Ong
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News |
Chatbot AI makes racist judgements on the basis of dialect
Some large language models harbour hidden biases that cannot be removed using standard methods.
- Elizabeth Gibney
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Article
| Open AccessBlueprinting extendable nanomaterials with standardized protein blocks
A study describes an approach using designed building blocks that are far more regular in geometry than natural proteins to construct modular multicomponent protein assemblies.
- Timothy F. Huddy
- , Yang Hsia
- & David Baker
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Article
| Open AccessSpatially organized cellular communities form the developing human heart
Combining single-cell RNA-sequencing with high-resolution multiplexed error-robust fluorescence in situ hybridization reveals in detail the cellular interactions and specialization of cardiac cell types that form and remodel the human heart.
- Elie N. Farah
- , Robert K. Hu
- & Neil C. Chi
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Correspondence |
Embrace AI to break down barriers in publishing for people who aren’t fluent in English
- Charles Morphy D. Santos
- & João Paulo Gois
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Technology Feature |
No installation required: how WebAssembly is changing scientific computing
Enabling code execution in the web browser, the multilanguage tool is powerful but complicated.
- Jeffrey M. Perkel
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News |
Could AI-designed proteins be weaponized? Scientists lay out safety guidelines
AI tools that can come up with protein structures at the push of a button should be used safely and ethically, say researchers in the field.
- Ewen Callaway
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News Explainer |
AI-generated images and video are here: how could they shape research?
Scientists are already using image-generating models to jazz up papers and presentations. But some say these tools could harm research.
- Carissa Wong
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Editorial |
Why scientists trust AI too much — and what to do about it
Some researchers see superhuman qualities in artificial intelligence. All scientists need to be alert to the risks this creates.
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Article
| Open AccessDecoding chromatin states by proteomic profiling of nucleosome readers
A multidimensional proteomics analysis of the interactions between around 2,000 nuclear proteins and over 80 modified dinucleosomes representing promoter, enhancer and heterochromatin states provides insights into how chromatin states are decoded by chromatin readers.
- Saulius Lukauskas
- , Andrey Tvardovskiy
- & Till Bartke
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World View |
Here’s what many digital tools for chronic pain are doing wrong
To address the chronic-pain crisis, digital health technologies must break out of their silos and become integrative and holistic.
- Benjamin Lipp
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News Explainer |
Is ChatGPT making scientists hyper-productive? The highs and lows of using AI
Large language models are transforming scientific writing and publishing. But the productivity boost that these tools bring could have a downside.
- McKenzie Prillaman
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Article
| Open AccessAutomated model building and protein identification in cryo-EM maps
ModelAngelo builds atomic models and identifies proteins with unknown sequences in cryo-EM maps.
- Kiarash Jamali
- , Lukas Käll
- & Sjors H. W. Scheres
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Article
| Open AccessPrevalence of persistent SARS-CoV-2 in a large community surveillance study
Using viral sequence data, individuals with persistent SARS-CoV-2 infections were identified, and had higher odds of self-reporting long COVID, in a large community surveillance study.
- Mahan Ghafari
- , Matthew Hall
- & Katrina Lythgoe
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Correspondence |
Stockholm declaration on AI ethics: why others should sign
- Ross D. King
- , Teresa Scassa
- & Hiroaki Kitano
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World View |
Generative AI’s environmental costs are soaring — and mostly secret
First-of-its-kind US bill would address the environmental costs of the technology, but there’s a long way to go.
- Kate Crawford
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Article
| Open AccessGenetic drivers of heterogeneity in type 2 diabetes pathophysiology
A meta-analysis of genome-wide association studies of type 2 diabetes (T2D) identifies more than 600 T2D-associated loci; integrating physiological trait and single-cell chromatin accessibility data at these loci sheds light on heterogeneity within the T2D phenotype.
- Ken Suzuki
- , Konstantinos Hatzikotoulas
- & Eleftheria Zeggini
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Article
| Open AccessGenomic data in the All of Us Research Program
A study describes the release of clinical-grade whole-genome sequence data for 245,388 diverse participants by the All of Us Research Program and characterizes the properties of the dataset.
- Alexander G. Bick
- , Ginger A. Metcalf
- & Joshua C. Denny
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News Explainer |
What the EU’s tough AI law means for research and ChatGPT
The EU AI Act is the world’s first major legislation on artificial intelligence and strictly regulates general-purpose models.
- Elizabeth Gibney
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News Explainer |
How journals are fighting back against a wave of questionable images
Publishers are deploying AI-based tools to detect suspicious images, but generative AI threatens their efforts.
- Nicola Jones
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News |
Apple Vision Pro: what does it mean for scientists?
The headset opens up possibilities in accessibility and medical research — and raises concerns about human behaviour.
- Jonathan O'Callaghan
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News |
AI chatbot shows surprising talent for predicting chemical properties and reactions
Researchers lightly tweak ChatGPT-like system to offer chemistry insight.
- Davide Castelvecchi
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Career Column |
‘Obviously ChatGPT’ — how reviewers accused me of scientific fraud
A journal reviewer accused Lizzie Wolkovich of using ChatGPT to write a manuscript. She hadn’t — but her paper was rejected anyway.
- E. M. Wolkovich
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News |
First passages of rolled-up Herculaneum scroll revealed
Researchers used artificial intelligence to decipher the text of 2,000-year-old charred papyrus scripts, unveiling musings on music and capers.
- Jo Marchant
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Career Column |
In the AI science boom, beware: your results are only as good as your data
Machine-learning systems are voracious data consumers — but trustworthy results require more vetting both before and after publication.
- Hunter Moseley
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News |
This AI learnt language by seeing the world through a baby’s eyes
A neural network that taught itself to recognize objects using the filmed experiences of a single infant could offer new insights into how humans learn.
- Elizabeth Gibney
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Editorial |
How can scientists make the most of the public’s trust in them?
Researchers have a part to play in addressing concerns about government interference in science.
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Article |
Conformational ensembles of the human intrinsically disordered proteome
A computational model generates conformational ensembles of 28,058 intrinsically disordered proteins and regions (IDRs) in the human proteome and sheds light on the relationship between sequence, conformational properties and functions of IDRs.
- Giulio Tesei
- , Anna Ida Trolle
- & Kresten Lindorff-Larsen
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Article
| Open AccessSHR and SCR coordinate root patterning and growth early in the cell cycle
Quantitative time-resolved microscopy analysis of SHR and SCR dynamics in single cells of living Arabidopsis roots shows that these transcription factors coordinate formative and proliferative cell divisions early in the cell cycle.
- Cara M. Winter
- , Pablo Szekely
- & Philip N. Benfey
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Outlook |
Tracking down tuberculosis
Improvements in screening and diagnosis could help to eradicate this curable disease.
- Neil Savage
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Correspondence |
Tech developers must respect equitable AI access
- Michał Choraś
- , Marek Pawlicki
- & Aleksandra Pawlicka
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Editorial |
Computers make mistakes and AI will make things worse — the law must recognize that
A tragic scandal at the UK Post Office highlights the need for legal change, especially as organizations embrace artificial intelligence to enhance decision-making.
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News |
Two-faced AI language models learn to hide deception
‘Sleeper agents’ seem benign during testing but behave differently once deployed. And methods to stop them aren’t working.
- Matthew Hutson
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Technology Feature |
Seven technologies to watch in 2024
Advances in artificial intelligence are at the heart of many of this year’s most exciting areas of technological innovation
- Michael Eisenstein
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News |
This robot grows like a vine — and could help navigate disaster zones
Plant-inspired machines could one day prove useful in search-and-rescue scenarios.
- Davide Castelvecchi
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News |
AlphaFold found thousands of possible psychedelics. Will its predictions help drug discovery?
Researchers have doubted how useful the AI protein-structure tool will be in discovering medicines — now they are learning how to deploy it effectively.
- Ewen Callaway
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News |
DeepMind AI solves geometry problems at star-student level
Algorithms are now as good at geometry as some of the world’s most mathematically talented school kids.
- Davide Castelvecchi
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Correspondence |
Does generative AI help academics to do more or less?
- Richard Watermeyer
- , Donna Lanclos
- & Lawrie Phipps
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Correspondence |
Centres of Excellence in AI for global health equity — a strategic vision for LMICs
- Hossein Akbarialiabad
- & Nelson K. Sewankambo
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News |
Google AI has better bedside manner than human doctors — and makes better diagnoses
Researchers say their artificial-intelligence system could help to democratize medicine.
- Mariana Lenharo
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News |
‘Set it and forget it’: automated lab uses AI and robotics to improve proteins
A self-driving lab system spent half a year engineering enzymes to work at higher temperatures.
- Ewen Callaway
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News |
Medical AI falters when assessing patients it hasn’t seen
Physicians rely on algorithms for personalized medicine — but an analysis of schizophrenia trials shows that the tools fail to adapt to new data sets.
- Miryam Naddaf
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Editorial |
There are holes in Europe’s AI Act — and researchers can help to fill them
Scientists have been promised a front-row seat for the formulation of the EU’s proposed AI regulatory structures. They should seize this opportunity to bridge some big gaps.
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News Feature |
The AI–quantum computing mash-up: will it revolutionize science?
Scientists are exploring the potential of quantum machine learning. But whether there are useful applications for the fusion of artificial intelligence and quantum computing is unclear.
- Davide Castelvecchi
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News |
Will superintelligent AI sneak up on us? New study offers reassurance
Improvements in the performance of large language models such as ChatGPT are more predictable than they seem.
- Matthew Hutson
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News & Views |
Large language models direct automated chemistry laboratory
Automation of chemistry research has focused on developing robots to execute jobs. Artificial-intelligence technology has now been used not only to control robots, but also to plan their tasks on the basis of simple human prompts.
- Ana Laura Dias
- & Tiago Rodrigues
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