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| Open AccessStructure–function analysis of histone H2B and PCNA ubiquitination dynamics using deubiquitinase-deficient strains
- Kaitlin S. Radmall
- , Prakash K. Shukla
- & Mahesh B. Chandrasekharan
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| Open AccessCalcineurin-mediated dephosphorylation enhances the stability and transactivation of c-Myc
- Takahiro Masaki
- , Makoto Habara
- & Midori Shimada
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| Open AccessDetection, visualization and quantification of protein complexes in human Alzheimer’s disease brains using proximity ligation assay
- Wilber Romero-Fernandez
- , Cristian Carvajal-Tapia
- & Matthew S. Schrag
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| Open AccessFMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin–proteasome system
- Hideo Shimizu
- & Hirohiko Hohjoh
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| Open AccessDisruption of male fertility-critical Dcaf17 dysregulates mouse testis transcriptome
- Raed Abu-Dawud
- , Bhavesh V. Mistry
- & Abdullah M. Assiri
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| Open AccessProteome-wide profiling and mapping of post translational modifications in human hearts
- Navratan Bagwan
- , Henrik H. El Ali
- & Alicia Lundby
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| Open AccessFunctional impacts of the ubiquitin–proteasome system on DNA damage recognition in global genome nucleotide excision repair
- Wataru Sakai
- , Mayumi Yuasa-Sunagawa
- & Kaoru Sugasawa
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| Open AccessGfi1 upregulates c-Myc expression and promotes c-Myc-driven cell proliferation
- Yangyang Zhang
- & Fan Dong
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| Open AccessOTUD4 enhances TGFβ signalling through regulation of the TGFβ receptor complex
- Patrick William Jaynes
- , Prasanna Vasudevan Iyengar
- & Pieter Johan Adam Eichhorn
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| Open AccessSubstitution of Thr572 to Ala in mouse c-Myb attenuates progression of early erythroid differentiation
- Kyoko Kitagawa
- , Chiharu Uchida
- & Masatoshi Kitagawa
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| Open AccessMG132 exerts anti-viral activity against HSV-1 by overcoming virus-mediated suppression of the ERK signaling pathway
- Hanako Ishimaru
- , Kohei Hosokawa
- & Masahiro Fujimuro
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| Open AccessGenome-wide screening reveals a role for subcellular localization of CRBN in the anti-myeloma activity of pomalidomide
- Shumpei Tateno
- , Midori Iida
- & Yuki Yamaguchi
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| Open AccessIdentification of a novel trigger complex that facilitates ribosome-associated quality control in mammalian cells
- Satoshi Hashimoto
- , Takato Sugiyama
- & Toshifumi Inada
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| Open AccessMitochondrial MUL1 E3 ubiquitin ligase regulates Hypoxia Inducible Factor (HIF-1α) and metabolic reprogramming by modulating the UBXN7 cofactor protein
- Lucia Cilenti
- , Jacopo Di Gregorio
- & Antonis S. Zervos
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| Open AccessTargeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation
- Sylwia Jones
- , Peter J. King
- & Daniel Hochhauser
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| Open AccessInflammatory bowel disease-associated ubiquitin ligase RNF183 promotes lysosomal degradation of DR5 and TRAIL-induced caspase activation
- Yan Wu
- , Yuka Kimura
- & Masayuki Kaneko
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| Open AccessA negative feedback mechanism links UBC gene expression to ubiquitin levels by affecting RNA splicing rather than transcription
- Marzia Bianchi
- , Rita Crinelli
- & Mauro Magnani
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| Open AccessUbiquitylation and endocytosis of the human LAT1/SLC7A5 amino acid transporter
- Céline Barthelemy
- & Bruno André
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| Open AccessRNF34 overexpression exacerbates neurological deficits and brain injury in a mouse model of intracerebral hemorrhage by potentiating mitochondrial dysfunction-mediated oxidative stress
- Xin Qu
- , Ning Wang
- & Weitao Cheng
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| Open AccessDifferential Inhibition of Human and Trypanosome Ubiquitin E1S by TAK-243 Offers Possibilities for Parasite Selective Inhibitors
- D. Roeland Boer
- & Marie-José Bijlmakers
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| Open AccessSQSTM-1/p62 potentiates HTLV-1 Tax-mediated NF-κB activation through its ubiquitin binding function
- Aurélien Schwob
- , Elodie Teruel
- & Chloé Journo
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| Open AccessMechanism and Consequences of The Impaired Hif-1α Response to Hypoxia in Human Proximal Tubular HK-2 Cells Exposed to High Glucose
- Coral García-Pastor
- , Selma Benito-Martínez
- & Francisco Javier Lucio-Cazaña
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| Open AccessUbiquitin receptors are required for substrate-mediated activation of the proteasome’s unfolding ability
- Mary D. Cundiff
- , Christina M. Hurley
- & Daniel A. Kraut
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| Open AccessMultilevel structure–activity profiling reveals multiple green tea compound families that each modulate ubiquitin-activating enzyme and ubiquitination by a distinct mechanism
- Gabriel Fenteany
- , Paras Gaur
- & Lajos Haracska
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| Open AccessProximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins
- Sascha E. Dho
- , Nancy Silva-Gagliardi
- & C. Jane McGlade
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| Open AccessNuclear and cytoplasmic WDR-23 isoforms mediate differential effects on GEN-1 and SKN-1 substrates
- Brett N. Spatola
- , Jacqueline Y. Lo
- & Sean P. Curran
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| Open AccessUncoupling of p97 ATPase activity has a dominant negative effect on protein extraction
- Halley B. Rycenga
- , Kelly B. Wolfe
- & David T. Long
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| Open AccessThe mammalian CTLH complex is an E3 ubiquitin ligase that targets its subunit muskelin for degradation
- Matthew E. R. Maitland
- , Gabriel Onea
- & Caroline Schild-Poulter
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| Open AccessNeuralized family member NEURL1 is a ubiquitin ligase for the cGMP-specific phosphodiesterase 9A
- Kati Taal
- , Jürgen Tuvikene
- & Tõnis Timmusk
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| Open AccessStructural basis of βTrCP1-associated GLI3 processing
- Shagufta Shafique
- & Sajid Rashid
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| Open AccessDisruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis
- Turgay Saritas
- , Catherina A. Cuevas
- & James A. McCormick
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| Open AccessGlobal Ubiquitome Profiling Revealed the Roles of Ubiquitinated Proteins in Metabolic Pathways of Tea Leaves in Responding to Drought Stress
- Hui Xie
- , Yu Wang
- & Zhaotang Ding
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| Open AccessKBTBD11, a novel BTB-Kelch protein, is a negative regulator of osteoclastogenesis through controlling Cullin3-mediated ubiquitination of NFATc1
- Shun Narahara
- , Eiko Sakai
- & Takayuki Tsukuba
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| Open AccessVangl2 interaction plays a role in the proteasomal degradation of Prickle2
- Tadahiro Nagaoka
- , Mikio Furuse
- & Masashi Kishi
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| Open AccessThe circadian E3 ligase complex SCFFBXL3+CRY targets TLK2
- Stephanie Papp Correia
- , Alanna B. Chan
- & Katja A. Lamia
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| Open AccessThe E3 ubiquitin ligase Trim13 regulates Nur77 stability via casein kinase 2α
- Bin Huang
- , Han Zhong Pei
- & Suk-Hwan Baek
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| Open AccessStructural insights into ubiquitin phosphorylation by PINK1
- Kei Okatsu
- , Yusuke Sato
- & Shuya Fukai
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| Open AccessExpression and Regulation of Deubiquitinase-Resistant, Unanchored Ubiquitin Chains in Drosophila
- Jessica R. Blount
- , Kozeta Libohova
- & Sokol V. Todi
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| Open AccessHerpesviruses possess conserved proteins for interaction with Nedd4 family ubiquitin E3 ligases
- Tetsuo Koshizuka
- , Takahiro Kobayashi
- & Tatsuo Suzutani
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| Open AccessTemporal downregulation of the polyubiquitin gene Ubb affects neuronal differentiation, but not maturation, in cells cultured in vitro
- Byung-Kwon Jung
- , Chul-Woo Park
- & Kwon-Yul Ryu
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| Open AccessDynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies
- Katrin Juenemann
- , Anne H. P. Jansen
- & Eric A. Reits
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| Open AccessBeta-catenin cleavage enhances transcriptional activation
- Tatiana Goretsky
- , Emily M. Bradford
- & Terrence A. Barrett
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| Open AccessDeterminants of E2-ubiquitin conjugate recognition by RBR E3 ligases
- Luigi Martino
- , Nicholas R. Brown
- & Katrin Rittinger
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| Open AccessDNA damage-induced histone H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway
- I. K. Mandemaker
- , L. van Cuijk
- & J. A. Marteijn
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| Open AccessImpaired oxidative stress response characterizes HUWE1-promoted X-linked intellectual disability
- Matthias Bosshard
- , Rossana Aprigliano
- & Barbara van Loon
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| Open AccessComprehensive profiling of lysine ubiquitome reveals diverse functions of lysine ubiquitination in common wheat
- Ning Zhang
- , Lingran Zhang
- & Feng Chen
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| Open AccessMultiple regulatory mechanisms of the biological function of NRF3 (NFE2L3) control cancer cell proliferation
- A. M. Masudul Azad Chowdhury
- , Hiroki Katoh
- & Akira Kobayashi
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| Open AccessThe Role of Ubiquitination and Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate in the Degradation of the Adrenomedullin Type I Receptor
- Benoît T. Roux
- , Claudia C. Bauer
- & Graeme S. Cottrell
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| Open AccessHyper-O-GlcNAcylation induces cisplatin resistance via regulation of p53 and c-Myc in human lung carcinoma
- Sudjit Luanpitpong
- , Paweorn Angsutararux
- & Surapol Issaragrisil