Article
|
Open Access
Featured
-
-
Article
| Open AccessAhnak promotes tumor metastasis through transforming growth factor-β-mediated epithelial-mesenchymal transition
- Mira Sohn
- , Sunmee Shin
- & Yun Soo Bae
-
Article
| Open AccessDifferential requirement for dimerization partner DP between E2F-dependent activation of tumor suppressor and growth-related genes
- Hideyuki Komori
- , Yasuko Goto
- & Kiyoshi Ohtani
-
Article
| Open AccessPatient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation
- Paul Mellor
- , Jeremy D. S. Marshall
- & Deborah H. Anderson
-
Article
| Open AccessPKC Dependent p14ARF Phosphorylation on Threonine 8 Drives Cell Proliferation
- Rosa Fontana
- , Daniela Guidone
- & Maria Vivo
-
Article
| Open AccessZFP226 is a novel artificial transcription factor for selective activation of tumor suppressor KIBRA
- Katrin Schelleckes
- , Boris Schmitz
- & Eva Brand
-
Article
| Open AccessThe novel dithiocarbamate, DpdtC suppresses HER2-overexpressed cancer cells by up-regulating NDRG1 via inactivation of HER2-ERK 1/2 signaling
- Yun Yang
- , Youxun Liu
- & Changzheng Li
-
Article
| Open AccessExtracellular cholesterol oxidase production by Streptomyces aegyptia, in vitro anticancer activities against rhabdomyosarcoma, breast cancer cell-lines and in vivo apoptosis
- Noura El-Ahmady El-Naggar
- , Hoda M. Soliman
- & Nancy M. El-Shweihy
-
Article
| Open AccessFunctional loss of p53 cooperates with the in vivo microenvironment to promote malignant progression of gastric cancers
- Junko Ohtsuka
- , Hiroko Oshima
- & Rieko Ohki
-
Article
| Open AccessEstablishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation
- Tsuneo Ikenoue
- , Yumi Terakado
- & Yoichi Furukawa
-
Article
| Open AccessThe suppressive role of calcium sensing receptor in endometrial cancer
- Xiaoyan Xin
- , Xianqin Zeng
- & Hongbo Wang
-
Article
| Open AccessConjunction of potential G-quadruplex and adjacent cis-elements in the 5′ UTR of hepatocyte nuclear factor 4-alpha strongly inhibit protein expression
- Shangdong Guo
- & Hong Lu
-
Article
| Open AccessDual-specificity phosphatase 5 acts as an anti-inflammatory regulator by inhibiting the ERK and NF-κB signaling pathways
- Huiyun Seo
- , Young-Chang Cho
- & Sayeon Cho
-
Article
| Open AccessKIF1Bβ increases ROS to mediate apoptosis and reinforces its protein expression through O 2 − in a positive feedback mechanism in neuroblastoma
- Clara Angelina
- , Irene Sze Ying Tan
- & Zhi Xiong Chen
-
Article
| Open AccessThe responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation
- Linda Smith
- , Raed Farzan
- & David W. Meek
-
Article
| Open AccessEnforced GFI1 expression impedes human and murine leukemic cell growth
- Judith M. Hönes
- , Aniththa Thivakaran
- & Cyrus Khandanpour
-
Article
| Open AccessSIM2l attenuates resistance to hypoxia and tumor growth by transcriptional suppression of HIF1A in uterine cervical squamous cell carcinoma
- Kanako Nakamura
- , Masayuki Komatsu
- & Hiroki Sasaki
-
Article
| Open AccessAntitumor activities of Liver-targeting peptide modified Recombinant human Endostatin in BALB/c-nu mice with Hepatocellular carcinoma
- Ma Yan
- , Bao Dongmei
- & Zhu Jiayong
-
Article
| Open AccessNectin-like molecule-4/cell adhesion molecule 4 inhibits the ligand-induced dimerization of ErbB3 with ErbB2
- Kiyohito Mizutani
- , Shin Kedashiro
- & Yoshimi Takai
-
Article
| Open AccessMIER3 suppresses colorectal cancer progression by down-regulating Sp1, inhibiting epithelial-mesenchymal transition
- Man Peng
- , Yukun Hu
- & Jun Zhou
-
Article
| Open AccessLoss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer
- Tilak Khanal
- , Kwangmin Choi
- & Kyounghyun Kim
-
Article
| Open AccessDDX3 localizes to the centrosome and prevents multipolar mitosis by epigenetically and translationally modulating p53 expression
- Wei-Ju Chen
- , Wei-Ting Wang
- & Yan-Hwa Wu Lee
-
Article
| Open AccessHypoxia-inducible ERO1α promotes cancer progression through modulation of integrin-β1 modification and signalling in HCT116 colorectal cancer cells
- Norio Takei
- , Akihiro Yoneda
- & Yasuaki Tamura
-
Article
| Open AccessMyst2/Kat7 histone acetyltransferase interaction proteomics reveals tumour-suppressor Niam as a novel binding partner in embryonic stem cells
- Mercedes Pardo
- , Lu Yu
- & Jyoti S. Choudhary
-
Article
| Open AccessAnalysis of somatic mutations across the kinome reveals loss-of-function mutations in multiple cancer types
- Runjun D. Kumar
- & Ron Bose
-
Article
| Open AccessVGLL4 Selectively Represses YAP-Dependent Gene Induction and Tumorigenic Phenotypes in Breast Cancer
- Yinglong Zhang
- , He Shen
- & Jianmin Zhang
-
Article
| Open AccessThe essential role of TAp73 in bortezomib-induced apoptosis in p53-deficient colorectal cancer cells
- Yasamin Dabiri
- , Sara Kalman
- & Xinlai Cheng
-
Article
| Open AccessQuantitative proteomics reveal the anti-tumour mechanism of the carbohydrate recognition domain of Galectin-3 in Hepatocellular carcinoma
- Mingchao Wang
- , Fang Tian
- & Xiaohong Qian
-
Article
| Open AccessDownregulated USP3 mRNA functions as a competitive endogenous RNA of SMAD4 by sponging miR-224 and promotes metastasis in colorectal cancer
- Zaozao Wang
- , Jie Yang
- & Xiangqian Su
-
Article
| Open AccessThe role of SET/I2PP2A in canine mammary tumors
- Satoru Kake
- , Shunya Tsuji
- & Koichi Sato
-
Article
| Open AccessNKX6.3 Regulates Reactive Oxygen Species Production by Suppressing NF-kB and DNMT1 Activities in Gastric Epithelial Cells
- Jung Hwan Yoon
- , Olga Kim
- & Won Sang Park
-
Article
| Open AccessSecreted Frizzled-related protein 4 (sFRP4) chemo-sensitizes cancer stem cells derived from human breast, prostate, and ovary tumor cell lines
- A. Deshmukh
- , S. Kumar
- & A. Dharmarajan
-
Article
| Open AccessExcitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells
- Gregor Mönke
- , Elena Cristiano
- & Alexander Loewer
-
Article
| Open AccesssTRAIL-iRGD is a promising therapeutic agent for gastric cancer treatment
- Ying Huang
- , Xihan Li
- & Baorui Liu
-
Article
| Open AccessAlkaline ceramidase 2 is a novel direct target of p53 and induces autophagy and apoptosis through ROS generation
- Yitao Wang
- , Chunxue Zhang
- & Youquan Bu
-
Article
| Open AccessELF5-Mediated AR Activation Regulates Prostate Cancer Progression
- Kai Li
- , Yongmin Guo
- & Yong Xu
-
Article
| Open AccessNucleophosmin Interacts with PIN2/TERF1-interacting Telomerase Inhibitor 1 (PinX1) and Attenuates the PinX1 Inhibition on Telomerase Activity
- Derek Hang-Cheong Cheung
- , Sai-Tim Ho
- & Pang-Chui Shaw
-
Article
| Open AccessUbiquitin-specific peptidase 48 regulates Mdm2 protein levels independent of its deubiquitinase activity
- Kateřina Cetkovská
- , Hana Šustová
- & Stjepan Uldrijan
-
Article
| Open AccessLoss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway
- Jie Liu
- , Juan Li
- & Peijun Liu
-
Article
| Open AccessRNA helicase DDX3 maintains lipid homeostasis through upregulation of the microsomal triglyceride transfer protein by interacting with HNF4 and SHP
- Tsung-Yuan Tsai
- , Wei-Ting Wang
- & Yan-Hwa Wu Lee
-
Article
| Open AccessLoss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling
- Shamik Das
- , William P. Jackson
- & Lalita A. Shevde
-
Article
| Open AccessSomatostatin receptor expression on von Hippel-Lindau-associated hemangioblastomas offers novel therapeutic target
- Saman Sizdahkhani
- , Michael J. Feldman
- & Prashant Chittiboina
-
Article
| Open AccessThe metastasis suppressor RARRES3 as an endogenous inhibitor of the immunoproteasome expression in breast cancer cells
- Alison M. Anderson
- , Murugan Kalimutho
- & Mark A. Ragan
-
Article
| Open AccessThe C-terminus of IGFBP-5 suppresses tumor growth by inhibiting angiogenesis
- Jae Ryoung Hwang
- , Young-Jae Cho
- & Jeong-Won Lee
-
Article
| Open Accessp53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway
- Derek A. Franklin
- , Yizhou He
- & Yanping Zhang
-
Article
| Open AccessRETRACTED ARTICLE: Oncogenic transformation of human lung bronchial epithelial cells induced by arsenic involves ROS-dependent activation of STAT3-miR-21-PDCD4 mechanism
- Poyil Pratheeshkumar
- , Young-Ok Son
- & Xianglin Shi
-
Article
| Open AccessInsulin-IGF signaling affects cell transformation in the BALB/c 3T3 cell model
- Doerte Poburski
- , Christiane Leovsky
- & René Thierbach
-
Article
| Open AccessSulforaphane, a natural component of broccoli, inhibits vestibular schwannoma growth in vitro and in vivo
- Bo Gyung Kim
- , Takeshi Fujita
- & Jong Dae Lee
-
Article
| Open AccessLMO2 attenuates tumor growth by targeting the Wnt signaling pathway in breast and colorectal cancer
- Ye Liu
- , Di Huang
- & Wei Sun
-
Article
| Open AccessSMAR1 binds to T(C/G) repeat and inhibits tumor progression by regulating miR-371-373 cluster
- Jinumary Mathai
- , Smriti P. K. Mittal
- & Samit Chattopadhyay