Featured
-
-
Article
| Open Access
Rosa26-LSL-dCas9-VPR: a versatile mouse model for tissue specific and simultaneous activation of multiple genes for drug discovery
- Dalia Pakalniškytė
- , Tanja Schönberger
- & Martin Lenter
-
Article
| Open Access
Voltage imaging in the olfactory bulb using transgenic mouse lines expressing the genetically encoded voltage indicator ArcLight
- Jelena Platisa
- , Hongkui Zeng
- & Douglas A. Storace
-
Article
| Open Access
A deterministic genotyping workflow reduces waste of transgenic individuals by two-thirds
- Frederic Strobl
- & Ernst H. K. Stelzer
-
Article
| Open Access
Multiview deconvolution approximation multiphoton microscopy of tissues and zebrafish larvae
- Dimitrios Kapsokalyvas
- , Rodrigo Rosas
- & Marc A. M. J. van Zandvoort
-
Article
| Open Access
Identification of the Wallenda JNKKK as an Alk suppressor reveals increased competitiveness of Alk-expressing cells
- Georg Wolfstetter
- , Kathrin Pfeifer
- & Ruth H. Palmer
-
Article
| Open Access
A heritable profile of six miRNAs in autistic patients and mouse models
- Yusuf Ozkul
- , Serpil Taheri
- & Minoo Rassoulzadegan
-
Article
| Open Access
Impaired motor skill learning and altered seizure susceptibility in mice with loss or gain of function of the Kcnt1 gene encoding Slack (KNa1.1) Na+-activated K+ channels
- Imran H. Quraishi
- , Michael R. Mercier
- & Leonard K. Kaczmarek
-
Article
| Open Access
LIN28B affects gene expression at the hypothalamic-pituitary axis and serum testosterone levels
- Jaakko T. Leinonen
- , Yu-Chia Chen
- & Elisabeth Widén
-
Article
| Open Access
PGC-1β Induces Susceptibility To Acetaminophen-Driven Acute Liver Failure
- Elena Piccinin
- , Simon Ducheix
- & Antonio Moschetta
-
Article
| Open Access
Generation of genetically modified mice using SpCas9-NG engineered nuclease
- Wataru Fujii
- , Haruka Ito
- & Kunihiko Naito
-
Article
| Open Access
A novel zebrafish model to emulate lung injury by folate deficiency-induced swim bladder defectiveness and protease/antiprotease expression imbalance
- Gang-Hui Lee
- , Nai-Wei Cheng
- & Tzu-Fun Fu
-
Article
| Open Access
A new transgenic reporter line reveals Wnt-dependent Snai2 re-expression and cranial neural crest differentiation in Xenopus
- Jiejing Li
- , Mark Perfetto
- & Shuo Wei
-
Article
| Open Access
Simplified platform for mosaic in vivo analysis of cellular maturation in the developing heart
- Julie Goudy
- , Trevor Henley
- & Michael Bressan
-
Article
| Open Access
A synthetic male-specific sterilization system using the mammalian pro-apoptotic factor in a malaria vector mosquito
- Daisuke S. Yamamoto
- , Megumi Sumitani
- & Hirotomo Kato
-
Article
| Open Access
Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel development, but is dispensable for beta-cell and alpha-cell formation
- Chiara M. Toselli
- , Brayden M. Wilkinson
- & Timothy J. Kieffer
-
Article
| Open Access
A tRNA-based multiplex sgRNA expression system in zebrafish and its application to generation of transgenic albino fish
- Tomoya Shiraki
- & Koichi Kawakami
-
Article
| Open Access
Validation of control genes and a standardised protocol for quantifying gene expression in the livers of C57BL/6 and ApoE−/− mice
- Priscilla E. L. Day
- , Karen F. Chambers
- & Paul A. Kroon
-
Article
| Open Access
PrismPlus: a mouse line expressing distinct fluorophores in four different brain cell types
- Janak Gaire
- , Heui Chang Lee
- & Kevin J. Otto
-
Article
| Open Access
piRNA-like small RNAs are responsible for the maternal-specific knockdown in the ascidian Ciona intestinalis Type A
- Teruki Satoh
- , Takako Iitsuka
- & Yasunori Sasakura
-
Article
| Open Access
ATF4 overexpression induces early onset of hyperlipidaemia and hepatic steatosis and enhances adipogenesis in zebrafish
- Kun-Yun Yeh
- , Chi-Yu Lai
- & Guor Mour Her
-
Article
| Open Access
Efficient generation of conditional knockout mice via sequential introduction of lox sites
- Takuro Horii
- , Sumiyo Morita
- & Izuho Hatada
-
Article
| Open Access
Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development
- Miao Zhao
- , Parisa Rabieifar
- & Staffan Strömblad
-
Article
| Open Access
Development and Characterization of A Novel Prox1-EGFP Lymphatic and Schlemm’s Canal Reporter Rat
- Eunson Jung
- , Daniel Gardner
- & Young-Kwon Hong
-
Article
| Open Access
SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in vivo
- Hanna Pettersson
- , Behdad Zarnegar
- & Klas Kullander
-
Article
| Open Access
Inflammatory and Neuropathic Nociception is Preserved in GPR55 Knockout Mice
- Lawrence M. Carey
- , Tannia Gutierrez
- & Andrea G. Hohmann
-
Article
| Open Access
TALEN-mediated knock-in via non-homologous end joining in the crustacean Daphnia magna
- Takashi Nakanishi
- , Yasuhiko Kato
- & Hajime Watanabe
-
Article
| Open Access
Insertion of a knockout-first cassette in Ampd1 gene leads to neonatal death by disruption of neighboring genes expression
- Yongcheng Pan
- , Lusi Zhang
- & Jia-Da Li
-
Article
| Open Access
Efficient liver repopulation of transplanted hepatocyte prevents cirrhosis in a rat model of hereditary tyrosinemia type I
- Ludi Zhang
- , Yanjiao Shao
- & Lijian Hui
-
Article
| Open Access
Light-sheet microscopy imaging of a whole cleared rat brain with Thy1-GFP transgene
- Marzena Stefaniuk
- , Emilio J. Gualda
- & Leszek Kaczmarek
-
Article
| Open Access
PIERCE1 is critical for specification of left-right asymmetry in mice
- Young Hoon Sung
- , In-Jeoung Baek
- & Han-Woong Lee
-
Article
| Open Access
TGF-β Signaling Regulates Cementum Formation through Osterix Expression
- Hwajung Choi
- , Yu-Hyun Ahn
- & Eui-Sic Cho
-
Article
| Open Access
Zebrafish biosensor for toxicant induced muscle hyperactivity
- Maryam Shahid
- , Masanari Takamiya
- & Uwe Strähle
-
Article
| Open Access
Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas
- G. Pujadas
- , S. Cervantes
- & R. Gasa
-
Article
| Open Access
A novel resource for studying function and dysfunction of α-synuclein: mouse lines for modulation of endogenous Snca gene expression
- Natalia Ninkina
- , Natalie Connor-Robson
- & Vladimir L. Buchman
-
Article
| Open Access
Efficient Generation of Myostatin Mutations in Pigs Using the CRISPR/Cas9 System
- Kankan Wang
- , Hongsheng Ouyang
- & Daxin Pang
-
Article
| Open Access
Multiplexed 3D FRET imaging in deep tissue of live embryos
- Ming Zhao
- , Xiaoyang Wan
- & Leilei Peng
-
Article
| Open Access
Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression
- Amber L. Southwell
- , Stephen E.P. Smith
- & Michael R. Hayden
-
Article
| Open Access
Exposure to endosulfan influences sperm competition in Drosophila melanogaster
- Snigdha Misra
- , Ajay Kumar
- & Kristipati Ravi Ram
-
Article
| Open Access
Validation of microinjection methods for generating knockout mice by CRISPR/Cas-mediated genome engineering
- Takuro Horii
- , Yuji Arai
- & Izuho Hatada
-
Article
| Open Access
Enhanced efficiency of P-element mediated transgenesis in Drosophila: Microinjection of DNA complexed with nanomaterial
- Madhavi Sonane
- , Ritu Goyal
- & Kailash C. Gupta
-
Article
| Open Access
Production of biallelic CMP-Neu5Ac hydroxylase knock-out pigs
- Deug-Nam Kwon
- , Kiho Lee
- & Jin-Hoi Kim
-
Article
| Open Access
Germline excision of transgenes in Aedes aegypti by homing endonucleases
- Azadeh Aryan
- , Michelle A. E. Anderson
- & Zach N. Adelman
-
Article
| Open Access
Efficient gene targeting by TAL effector nucleases coinjected with exonucleases in zygotes
- Tomoji Mashimo
- , Takehito Kaneko
- & Tadao Serikawa
Improved selection of zebrafish CRISPR editing by early next-generation sequencing based genotyping