Featured
-
-
Article
| Open AccessStructure and mechanism of an antibiotics-synthesizing 3-hydroxykynurenine C-methyltransferase
- Sheng-Chia Chen
- , Chi-Hung Huang
- & Yeh Chen
-
Article
| Open Access3D Structural Fluctuation of IgG1 Antibody Revealed by Individual Particle Electron Tomography
- Xing Zhang
- , Lei Zhang
- & Gang Ren
-
Article
| Open AccessAuto-inhibitory Mechanism of the Human Mitochondrial RNase P Protein Complex
- Fengzhi Li
- , Xiaofen Liu
- & Yuequan Shen
-
Article
| Open AccessDeveloping the IVIG biomimetic, Hexa-Fc, for drug and vaccine applications
- Daniel M. Czajkowsky
- , Jan Terje Andersen
- & Richard J. Pleass
-
Article
| Open AccessStructural basis for cooperative oxygen binding and bracelet-assisted assembly of Lumbricus terrestris hemoglobin
- Wei-Ting Chen
- , Yu-Chuen Chen
- & Chih-Yu Chao
-
Article
| Open AccessMolecular basis for mid-region amyloid-β capture by leading Alzheimer's disease immunotherapies
- Gabriela A. N. Crespi
- , Stefan J. Hermans
- & Luke A. Miles
-
Article
| Open AccessA Dynamic View of ATP-coupled Functioning Cycle of Hsp90 N-terminal Domain
- Huaqun Zhang
- , Chen Zhou
- & Naixia Zhang
-
Article
| Open AccessA Quaternary Mechanism Enables the Complex Biological Functions of Octameric Human UDP-glucose Pyrophosphorylase, a Key Enzyme in Cell Metabolism
- Jana Indra Führing
- , Johannes Thomas Cramer
- & Roman Fedorov
-
Article
| Open AccessHidden relationships between metalloproteins unveiled by structural comparison of their metal sites
- Yana Valasatava
- , Claudia Andreini
- & Antonio Rosato
-
Article
| Open AccessStructure and function of a Clostridium difficile sortase enzyme
- Christopher J. Chambers
- , April K. Roberts
- & K. Ravi Acharya
-
Article
| Open AccessUsing size-selected gold clusters on graphene oxide films to aid cryo-transmission electron tomography alignment
- Kenton P. Arkill
- , Judith M. Mantell
- & Richard E. Palmer
-
Article
| Open AccessStructural conservation among the rhodopsin-like and other G protein-coupled receptors
- Mikitaka Kinoshita
- & Tetsuji Okada
-
Article
| Open AccessThe Glycan Role in the Glycopeptide Immunogenicity Revealed by Atomistic Simulations and Spectroscopic Experiments on the Multiple Sclerosis Biomarker CSF114(Glc)
- Agostino Bruno
- , Mario Scrima
- & Vittorio Limongelli
-
Article
| Open AccessRational stabilization of complex proteins: a divide and combine approach
- Emilio Lamazares
- , Isabel Clemente
- & Javier Sancho
-
Article
| Open AccessStructure, Function and Inhibition of the Phosphoethanolamine Methyltransferases of the Human Malaria Parasites Plasmodium vivax and Plasmodium knowlesi
- Aprajita Garg
- , Tiit Lukk
- & Choukri Ben Mamoun
-
Article
| Open AccessA Novel Mechanism for Small Heat Shock Proteins to Function as Molecular Chaperones
- Kaiming Zhang
- , Anastasia N. Ezemaduka
- & Chang-Cheng Yin
-
Article
| Open AccessNew Cyt-like δ-endotoxins from Dickeya dadantii: structure and aphicidal activity
- Karine Loth
- , Denis Costechareyre
- & Pedro da Silva
-
Article
| Open AccessSubstitution of tryptophan 89 with tyrosine switches the DNA binding mode of PC4
- Jinguang Huang
- , Yanxiang Zhao
- & You-Liang Peng
-
Article
| Open AccessStructure of human dipeptidyl peptidase 10 (DPPY): a modulator of neuronal Kv4 channels
- Gustavo Arruda Bezerra
- , Elena Dobrovetsky
- & Karl Gruber
-
Article
| Open AccessHDL surface lipids mediate CETP binding as revealed by electron microscopy and molecular dynamics simulation
- Meng Zhang
- , River Charles
- & Gang Ren
-
Article
| Open AccessCrystal structure of Gib2, a signal-transducing protein scaffold associated with ribosomes in Cryptococcus neoformans
- Rya Ero
- , Valya Tenusheva Dimitrova
- & Yong-Gui Gao
-
Article
| Open AccessDynamic association of PfEMP1 and KAHRP in knobs mediates cytoadherence during Plasmodium invasion
- Akshay Kumar Ganguly
- , Priyatosh Ranjan
- & Neel Sarovar Bhavesh
-
Article
| Open AccessStructural Basis for Substrate-specific Acetylation of Nα-acetyltransferase Ard1 from Sulfolobus solfataricus
- Yu-Yung Chang
- & Chun-Hua Hsu
-
Article
| Open AccessEfficient Demyristoylase Activity of SIRT2 Revealed by Kinetic and Structural Studies
- Yan-Bin Teng
- , Hui Jing
- & Quan Hao
-
Article
| Open AccessCrystal structure of VmoLac, a tentative quorum quenching lactonase from the extremophilic crenarchaeon Vulcanisaeta moutnovskia
- Julien Hiblot
- , Janek Bzdrenga
- & Mikael Elias
-
Article
| Open AccessThe molecular architecture of dihydropyrindine receptor/L-type Ca2+ channel complex
- Hongli Hu
- , Zhao Wang
- & Chang-Cheng Yin
-
Article
| Open AccessLive cell immunogold labelling of RNA polymerase II
- Igor Orlov
- , Andreas Schertel
- & Danièle Spehner
-
Article
| Open AccessExtended Loop Region of Hcp1 is Critical for the Assembly and Function of Type VI Secretion System in Burkholderia pseudomallei
- Yan Ting Lim
- , Chacko Jobichen
- & Yunn-Hwen Gan
-
Article
| Open AccessCrystal structure of UbiX, an aromatic acid decarboxylase from the psychrophilic bacterium Colwellia psychrerythraea that undergoes FMN-induced conformational changes
- Hackwon Do
- , Soo Jin Kim
- & Jun Hyuck Lee
-
Article
| Open AccessStructural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor
- Judit Osz
- , Alastair G. McEwen
- & Natacha Rochel
-
Article
| Open AccessSignal enhancement and Patterson-search phasing for high-spatial-resolution coherent X-ray diffraction imaging of biological objects
- Yuki Takayama
- , Saori Maki-Yonekura
- & Koji Yonekura
-
Article
| Open AccessStructure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway
- Joana Fraga
- , Ana Maranha
- & Sandra Macedo-Ribeiro
-
Article
| Open AccessMedian Modified Wiener Filter for nonlinear adaptive spatial denoising of protein NMR multidimensional spectra
- Carlo Vittorio Cannistraci
- , Ahmed Abbas
- & Xin Gao
-
Article
| Open AccessEquilibrated Atomic Models of Outward-Facing P-glycoprotein and Effect of ATP Binding on Structural Dynamics
- Lurong Pan
- & Stephen G. Aller
-
Article
| Open AccessAn ignored variable: solution preparation temperature in protein crystallization
- Rui-Qing Chen
- , Qin-Qin Lu
- & Da-Chuan Yin
-
Article
| Open AccessPIP2-dependent coupling is prominent in Kv7.1 due to weakened interactions between S4-S5 and S6
- Marina A. Kasimova
- , Mark A. Zaydman
- & Mounir Tarek
-
Article
| Open AccessA Tool Set to Map Allosteric Networks through the NMR Chemical Shift Covariance Analysis
- Stephen Boulton
- , Madoka Akimoto
- & Giuseppe Melacini
-
Article
| Open AccessStructural insight into substrate recognition by the endoplasmic reticulum folding-sensor enzyme: crystal structure of third thioredoxin-like domain of UDP-glucose:glycoprotein glucosyltransferase
- Tong Zhu
- , Tadashi Satoh
- & Koichi Kato
-
Article
| Open AccessUtilisation of adsorption and desorption for simultaneously improving protein crystallisation success rate and crystal quality
- Yun-Zhu Guo
- , Li-Hua Sun
- & Da-Chuan Yin
-
Article
| Open AccessCrystal structure of Escherichia coli YidC, a membrane protein chaperone and insertase
- Kaoru Kumazaki
- , Toshiki Kishimoto
- & Osamu Nureki
-
Article
| Open AccessGlobal connectivity of hub residues in Oncoprotein structures encodes genetic factors dictating personalized drug response to targeted Cancer therapy
- Venky Soundararajan
- & Murali Aravamudan
-
Article
| Open AccessCrystal structure and stable property of the cancer-associated heterotypic nucleosome containing CENP-A and H3.3
- Yasuhiro Arimura
- , Kazuyoshi Shirayama
- & Hitoshi Kurumizaka
-
Article
| Open AccessSelf-assembled monolayers improve protein distribution on holey carbon cryo-EM supports
- Joel R. Meyerson
- , Prashant Rao
- & Sriram Subramaniam
-
Article
| Open AccessDynamic multidrug recognition by multidrug transcriptional repressor LmrR
- Koh Takeuchi
- , Yuji Tokunaga
- & Ichio Shimada
-
Article
| Open AccessStructural Insight into the Central Element Assembly of the Synaptonemal Complex
- Jing Lu
- , Yanling Gu
- & Yuequan Shen
-
Article
| Open AccessTrimeric HIV Env provides epitope occlusion mediated by hypervariable loops
- Carlos G. Moscoso
- , Li Xing
- & R. Holland Cheng
-
Article
| Open AccessUnglycosylated recombinant human glutathione peroxidase 3 mutant from Escherichia coli is active as a monomer
- Jian Song
- , Yang Yu
- & Hongwei Song
-
Article
| Open AccessCrystal structure of the phosphate-binding protein (PBP-1) of an ABC-type phosphate transporter from Clostridium perfringens
- Daniel Gonzalez
- , Magali Richez
- & Mikael Elias
-
Article
| Open AccessStructure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum
- Wenting Liu
- , Xinxin Feng
- & Rey-Ting Guo