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Characterization of signal and transit peptides based on motif composition and taxon-specific patterns
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DARPins bind their cytosolic targets after having been translocated through the protective antigen pore of anthrax toxin
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Transport of Designed Ankyrin Repeat Proteins through reconstituted human bronchial epithelia and protection against SARS-CoV-2
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Hydrophobicity is a key determinant in the activity of arginine-rich cell penetrating peptides
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Activation of SIRT1 promotes membrane resealing via cortactin
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Twin-arginine translocase component TatB performs folding quality control via a chaperone-like activity
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Ipomoeassin-F disrupts multiple aspects of secretory protein biogenesis
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A human infertility-associated KASH5 variant promotes mitochondrial localization
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Clinically-identified C-terminal mutations in fibulin-3 are prone to misfolding and destabilization
- DaNae R. Woodard
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Identification of a nuclear localization signal in the Plasmodium falciparum CTP: phosphocholine cytidylyltransferase enzyme
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Transportin-2 plays a critical role in nucleocytoplasmic shuttling of oestrogen receptor-α
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TBC1D1 interacting proteins, VPS13A and VPS13C, regulate GLUT4 homeostasis in C2C12 myotubes
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Avicin G is a potent sphingomyelinase inhibitor and blocks oncogenic K- and H-Ras signaling
- Christian M. Garrido
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Epididymal proteins Binder of SPerm Homologs 1 and 2 (BSPH1/2) are dispensable for male fertility and sperm motility in mice
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Development of an experimental method of systematically estimating protein expression limits in HEK293 cells
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Active nuclear import of the deacetylase Sirtuin-2 is controlled by its C-terminus and importins
- Matthew J. G. Eldridge
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Endomembrane Protein Trafficking Regulated by a TvCyP2 Cyclophilin in the Protozoan Parasite, Trichomonas vaginalis
- Hong-Ming Hsu
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Contribution of syndecans to cellular uptake and fibrillation of α-synuclein and tau
- Anett Hudák
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ERICH3 in Primary Cilia Regulates Cilium Formation and the Localisations of Ciliary Transport and Sonic Hedgehog Signaling Proteins
- Mona Alsolami
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Activated α2-Macroglobulin Regulates LRP1 Levels at the Plasma Membrane through the Activation of a Rab10-dependent Exocytic Pathway in Retinal Müller Glial Cells
- Javier R. Jaldín-Fincati
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Endoplasmic reticulum stress disrupts lysosomal homeostasis and induces blockade of autophagic flux in human trophoblasts
- Akitoshi Nakashima
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14-3-3 signal adaptor and scaffold proteins mediate GPCR trafficking
- Luwa Yuan
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Rescue of tight junctional localization of a claudin-16 mutant D97S by antimalarial medicine primaquine in Madin-Darby canine kidney cells
- Kana Marunaka
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Role of the membrane potential in mitochondrial protein unfolding and import
- Takehiro K. Sato
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CALHM1/CALHM3 channel is intrinsically sorted to the basolateral membrane of epithelial cells including taste cells
- Makiko Kashio
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Myristoyl group-aided protein import into the mitochondrial intermembrane space
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Contribution of syndecans to cellular internalization and fibrillation of amyloid-β(1–42)
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The nuclear variant of bone morphogenetic protein 2 (nBMP2) is expressed in macrophages and alters calcium response
- Claudia M. Tellez Freitas
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A rare human CEP290 variant disrupts the molecular integrity of the primary cilium and impairs Sonic Hedgehog machinery
- Michaela B. C. Kilander
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PMLPR: A novel method for predicting subcellular localization based on recommender systems
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A novel triple combination of pharmacological chaperones improves F508del-CFTR correction
- Graeme W. Carlile
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LIM Protein Ajuba associates with the RPA complex through direct cell cycle-dependent interaction with the RPA70 subunit
- Sandy Fowler
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Cholinergic activity is essential for maintaining the anterograde transport of Choline Acetyltransferase in Drosophila - Swagata Dey
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Trafficking, localization and degradation of the Na+,HCO3− co-transporter NBCn1 in kidney and breast epithelial cells
- Christina Wilkens Olesen
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Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription
- Mareike Bütepage
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Yeast aconitase mitochondrial import is modulated by interactions of its C and N terminal domains and Ssa1/2 (Hsp70)
- Reut Ben-Menachem
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Membrane-association of EMR2/ADGRE2-NTF is regulated by site-specific N-glycosylation
- Yi-Shu Huang
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Molecular determinants of Guanylate Cyclase Activating Protein subcellular distribution in photoreceptor cells of the retina
- Santiago López-Begines
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Amnionless-mediated glycosylation is crucial for cell surface targeting of cubilin in renal and intestinal cells
- Tomohiro Udagawa
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Insulin-degrading enzyme is not secreted from cultured cells
- Eun Suk Song
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The peroxisome biogenesis factors posttranslationally target reticulon homology domain-containing proteins to the endoplasmic reticulum membrane
- Yasunori Yamamoto
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Unanticipated functional diversity among the TatA-type components of the Tat protein translocase
- Ekaterina Eimer
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- & Matthias Müller
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The interaction network of the YidC insertase with the SecYEG translocon, SRP and the SRP receptor FtsY
- Narcis-Adrian Petriman
- , Benjamin Jauß
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Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V
- Sarah C. Atkinson
- , Michelle D. Audsley
- & Natalie A. Borg
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Progesterone Via its Type-A Receptor Promotes Myometrial Gap Junction Coupling
- Lubna Nadeem
- , Oksana Shynlova
- & Stephen Lye
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A quantitative comparison of cytosolic delivery via different protein uptake systems
- Wouter P. R. Verdurmen
- , Marigona Mazlami
- & Andreas Plückthun
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An alternate mode of oligomerization for E. coli SecA
- Aliakbar Khalili Yazdi
- , Grant C. Vezina
- & Brian H. Shilton
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ROS induced distribution of mitochondria to filopodia by Myo19 depends on a class specific tryptophan in the motor domain
- Boris I. Shneyer
- , Marko Ušaj
- & Arnon Henn
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Retrograde trafficking of β-dystroglycan from the plasma membrane to the nucleus
- Viridiana Gracida-Jiménez
- , Ricardo Mondragón-González
- & Bulmaro Cisneros
Yeast 26S proteasome nuclear import is coupled to nucleus-specific degradation of the karyopherin adaptor protein Sts1