Article
|
Open Access
Featured
-
-
Article
| Open AccessDeep Analysis of Residue Constraints (DARC): identifying determinants of protein functional specificity
- Farzaneh Tondnevis
- , Elizabeth E. Dudenhausen
- & Andrew F. Neuwald
-
Article
| Open AccessIn silico Design of a Multivalent Vaccine Against Candida albicans
- Shikha Tarang
- , Varun Kesherwani
- & Michael D. Weston
-
Article
| Open AccessDomain-mediated interactions for protein subfamily identification
- Heetak Lee
- , Inhae Kim
- & Sanguk Kim
-
Article
| Open AccessMolecular dynamics simulation of the nanosecond pulsed electric field effect on kinesin nanomotor
- Jiří Průša
- & Michal Cifra
-
Article
| Open AccessStructural insight into conformational change in prion protein by breakage of electrostatic network around H187 due to its protonation
- Juhwan Lee
- & Iksoo Chang
-
Article
| Open AccessEvolutionary conservation of the intrinsic disorder-based Radical-Induced Cell Death1 hub interactome
- Lise Friis Christensen
- , Lasse Staby
- & Karen Skriver
-
Article
| Open AccessMolecular Dynamics Simulation reveals the mechanism by which the Influenza Cap-dependent Endonuclease acquires resistance against Baloxavir marboxil
- Ryunosuke Yoshino
- , Nobuaki Yasuo
- & Masakazu Sekijima
-
Article
| Open AccessParticle Mobility Analysis Using Deep Learning and the Moment Scaling Spectrum
- Marloes Arts
- , Ihor Smal
- & Erik Meijering
-
Article
| Open AccessExploring the limitations of biophysical propensity scales coupled with machine learning for protein sequence analysis
- Daniele Raimondi
- , Gabriele Orlando
- & Yves Moreau
-
Article
| Open AccessInvestigation of protein-protein interactions and hot spot region between PD-1 and PD-L1 by fragment molecular orbital method
- Hocheol Lim
- , Jungho Chun
- & Kyoung Tai No
-
Article
| Open AccessAmino acid substitution scoring matrices specific to intrinsically disordered regions in proteins
- Rakesh Trivedi
- & Hampapathalu Adimurthy Nagarajaram
-
Article
| Open AccessDeeper Profiles and Cascaded Recurrent and Convolutional Neural Networks for state-of-the-art Protein Secondary Structure Prediction
- Mirko Torrisi
- , Manaz Kaleel
- & Gianluca Pollastri
-
Article
| Open AccessStructure-based identification of a potential non-catalytic binding site for rational drug design in the fructose 1,6-biphosphate aldolase from Giardia lamblia
- Sara-Teresa Méndez
- , Adriana Castillo-Villanueva
- & Jesús Oria-Hernández
-
Article
| Open AccessStoichiogenomics reveal oxygen usage bias, key proteins and pathways associated with stomach cancer
- Xiaoyan Zuo
- , Bo Li
- & Yu-Juan Zhang
-
Article
| Open AccessComparative structural and evolutionary analyses predict functional sites in the artemisinin resistance malaria protein K13
- Romain Coppée
- , Daniel C. Jeffares
- & Jérôme Clain
-
Article
| Open AccessPhylogenetic and crystallographic analysis of Nostoc phycocyanin having blue-shifted spectral properties
- Ravi R. Sonani
- , Rajesh Prasad Rastogi
- & Datta Madamwar
-
Article
| Open AccessCompensated pathogenic variants in coagulation factors VIII and IX present complex mapping between molecular impact and hemophilia severity
- Òscar Marín
- , Josu Aguirre
- & Xavier de la Cruz
-
Article
| Open AccessComputational identification of microbial phosphorylation sites by the enhanced characteristics of sequence information
- Md. Mehedi Hasan
- , Md. Mamunur Rashid
- & Hiroyuki Kurata
-
Article
| Open AccessΑ Quantum Pattern Recognition Method for Improving Pairwise Sequence Alignment
- Konstantinos Prousalis
- & Nikos Konofaos
-
Article
| Open AccessWeb-based display of protein surface and pH-dependent properties for assessing the developability of biotherapeutics
- Max Hebditch
- & Jim Warwicker
-
Article
| Open AccessIdentification of non-specific Lipid Transfer Protein gene family members in Solanum lycopersicum and insights into the features of Sola l 3 protein
- Nunzio D’Agostino
- , Martina Buonanno
- & Maria Manuela Rigano
-
Article
| Open AccessPhoglyStruct: Prediction of phosphoglycerylated lysine residues using structural properties of amino acids
- Abel Chandra
- , Alok Sharma
- & Tatsuhiko Tsunoda
-
Article
| Open AccessReconstructing the evolutionary history of F420-dependent dehydrogenases
- M. Laura Mascotti
- , Hemant Kumar
- & Marco W. Fraaije
-
Article
| Open AccessRationalising drug delivery using nanoparticles: a combined simulation and immunology study of GnRH adsorbed to silica nanoparticles
- David J. Connell
- , Ayman Gebril
- & Paul A. Mulheran
-
Article
| Open AccessLarge-scale in-silico statistical mutagenesis analysis sheds light on the deleteriousness landscape of the human proteome
- Daniele Raimondi
- , Gabriele Orlando
- & Wim F. Vranken
-
Article
| Open AccessProteomics reveals ablation of PlGF increases antioxidant and neuroprotective proteins in the diabetic mouse retina
- Madhu Sudhana Saddala
- , Anton Lennikov
- & Hu Huang
-
Article
| Open AccessDesign of metalloproteins and novel protein folds using variational autoencoders
- Joe G. Greener
- , Lewis Moffat
- & David T Jones
-
Article
| Open AccessGlobal pentapeptide statistics are far away from expected distributions
- Jarosław Poznański
- , Jan Topiński
- & Marcin Grynberg
-
Article
| Open AccessPattern to Knowledge: Deep Knowledge-Directed Machine Learning for Residue-Residue Interaction Prediction
- Andrew K. C. Wong
- , Ho Yin Sze-To
- & Gary L. Johanning
-
Article
| Open AccessComparative Analysis of TM and Cytoplasmic β-barrel Conformations Using Joint Descriptor
- Jayaraman Thangappan
- , Sangwook Wu
- & Sun-Gu Lee
-
Article
| Open AccessPredictions of novel Schistosoma mansoni - human protein interactions consistent with experimental data
- J. White Bear
- , Thavy Long
- & James H. McKerrow
-
Article
| Open AccessPMLPR: A novel method for predicting subcellular localization based on recommender systems
- Elnaz Mirzaei Mehrabad
- , Reza Hassanzadeh
- & Changiz Eslahchi
-
Article
| Open AccessIDPpi: Protein-Protein Interaction Analyses of Human Intrinsically Disordered Proteins
- Vladimir Perovic
- , Neven Sumonja
- & Nevena Veljkovic
-
Article
| Open AccessStructural basis for cross-reactivity and conformation fluctuation of the major beech pollen allergen Fag s 1
- Adolfo H. Moraes
- , Claudia Asam
- & Ana Paula Valente
-
Article
| Open AccessGeometric compensation applied to image analysis of cell populations with morphological variability: a new role for a classical concept
- Joana Figueiredo
- , Isabel Rodrigues
- & João M. Sanches
-
Article
| Open AccessNew insights into the structural dynamics of the kinase JNK3
- Pankaj Mishra
- & Stefan Günther
-
Article
| Open AccessAssigning biological function using hidden signatures in cystine-stabilized peptide sequences
- S. M. Ashiqul Islam
- , Christopher Michel Kearney
- & Erich J. Baker
-
Article
| Open AccessInvestigation of immunogenic properties of Hemolin from silkworm, Bombyx mori as carrier protein: an immunoinformatic approach
- Veeranarayanan Surya Aathmanathan
- , Nattarsingam Jothi
- & Muthukalingan Krishnan
-
Article
| Open AccessEvolutionary convergence and divergence in archaeal chromosomal proteins and Chromo-like domains from bacteria and eukaryotes
- Gurmeet Kaur
- , Lakshminarayan M. Iyer
- & L. Aravind
-
Article
| Open AccessExploration of the effect of sequence variations located inside the binding pocket of HIV-1 and HIV-2 proteases
- Dhoha Triki
- , Telli Billot
- & Leslie Regad
-
Article
| Open AccessOn the contributing role of the transmembrane domain for subunit-specific sensitivity of integrin activation
- Giulia Pagani
- & Holger Gohlke
-
Article
| Open AccessAminode: Identification of Evolutionary Constraints in the Human Proteome
- Kevin T. Chang
- , Junyan Guo
- & Marco Sardiello
-
Article
| Open AccessAnalysis of the HIV-2 protease’s adaptation to various ligands: characterization of backbone asymmetry using a structural alphabet
- Dhoha Triki
- , Mario Enrique Cano Contreras
- & Leslie Regad
-
Article
| Open AccessUrothelial cancer proteomics provides both prognostic and functional information
- Guillermo de Velasco
- , Lucia Trilla-Fuertes
- & Daniel Castellano
-
Article
| Open AccessPLA2-like proteins myotoxic mechanism: a dynamic model description
- Rafael J. Borges
- , Ney Lemke
- & Marcos R. M. Fontes
-
Article
| Open AccessRandom protein sequences can form defined secondary structures and are well-tolerated in vivo
- Vyacheslav Tretyachenko
- , Jiří Vymětal
- & Klára Hlouchová
-
Article
| Open AccessHydrogen Bond Variations of Influenza A Viruses During Adaptation in Human
- Jiejian Luo
- , Lizong Deng
- & Taijiao Jiang
-
Article
| Open AccessStructural, physicochemical and dynamic features conserved within the aerolysin pore-forming toxin family
- Nuria Cirauqui
- , Luciano A. Abriata
- & Matteo Dal Peraro
-
Article
| Open AccessHighly diversified expansions shaped the evolution of membrane bound proteins in metazoans
- Misty M. Attwood
- , Arunkumar Krishnan
- & Helgi B. Schiöth