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| Open AccessOverexpression of mouse prion protein in transgenic mice causes a non-transmissible spongiform encephalopathy
- Graham S. Jackson
- , Jacqueline Linehan
- & John Collinge
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| Open AccessHereditary E200K mutation within the prion protein gene alters human iPSC derived cardiomyocyte function
- Aleksandar R. Wood
- , Simote T. Foliaki
- & Cathryn L. Haigh
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| Open AccessCharacteristic distribution and molecular properties of normal cellular prion protein in human endocrine and exocrine tissues
- Sachiko Koyama
- , Hideko Noguchi
- & Hiroyuki Honda
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| Open AccessA field-deployable diagnostic assay for the visual detection of misfolded prions
- Peter R. Christenson
- , Manci Li
- & Peter A. Larsen
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| Open AccessPrimary glia cells from bank vole propagate multiple rodent-adapted scrapie prions
- Karla A. Schwenke
- , Joo-Hee Wälzlein
- & Michael Beekes
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| Open AccessCanine D163-PrP polymorphic variant does not provide complete protection against prion infection in small ruminant PrP context
- Alba Marín-Moreno
- , Juan Carlos Espinosa
- & Juan María Torres
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| Open AccessNeurotropic influenza A virus infection causes prion protein misfolding into infectious prions in neuroblastoma cells
- Hideyuki Hara
- , Junji Chida
- & Suehiro Sakaguchi
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| Open AccessBank vole prion protein extends the use of RT-QuIC assays to detect prions in a range of inherited prion diseases
- Tze How Mok
- , Akin Nihat
- & Graham S. Jackson
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| Open AccessThe G127V variant of the prion protein interferes with dimer formation in vitro but not in cellulo
- Sudheer Babu Sangeetham
- , Anna Dorothee Engelke
- & Ervin Welker
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| Open AccessChronic wasting disease (CWD) prion detection in blood from pre-symptomatic white-tailed deer harboring PRNP polymorphic variants
- Carlos Kramm
- , Paulina Soto
- & Rodrigo Morales
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| Open AccessMixtures of prion substrains in natural scrapie cases revealed by ovinised murine models
- Tomás Barrio
- , Hicham Filali
- & Rosa Bolea
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| Open AccessNovel Strain of the Chronic Wasting Disease Agent Isolated From Experimentally Inoculated Elk With LL132 Prion Protein
- Jo Moore
- , Trudy Tatum
- & Justin Greenlee
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| Open AccessCo-existence of PrPD types 1 and 2 in sporadic Creutzfeldt-Jakob disease of the VV subgroup: phenotypic and prion protein characteristics
- Ignazio Cali
- , Gianfranco Puoti
- & Pierluigi Gambetti
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| Open AccessCharacterization of goat prions demonstrates geographical variation of scrapie strains in Europe and reveals the composite nature of prion strains
- Romolo Nonno
- , Alba Marin-Moreno
- & Jan P. M. Langeveld
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| Open AccessThermostability as a highly dependent prion strain feature
- Alba Marín-Moreno
- , Patricia Aguilar-Calvo
- & Juan María Torres
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| Open AccessGene-edited murine cell lines for propagation of chronic wasting disease prions
- Rupali Walia
- , Cheng Ching Ho
- & Hermann M. Schatzl
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| Open AccessEarly and Pre-Clinical Detection of Prion Seeding Activity in Cerebrospinal Fluid of Goats using Real-Time Quaking-Induced Conversion Assay
- Alessandra Favole
- , Maria Mazza
- & Cristiano Corona
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| Open AccessPMCA-replicated PrPD in urine of vCJD patients maintains infectivity and strain characteristics of brain PrPD: Transmission study
- Ignazio Cali
- , Jody Lavrich
- & Silvio Notari
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| Open AccessPressure Reveals Unique Conformational Features in Prion Protein Fibril Diversity
- Joan Torrent
- , Davy Martin
- & Human Rezaei
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| Open AccessDysregulation of autophagy in the central nervous system of sheep naturally infected with classical scrapie
- Óscar López-Pérez
- , Alicia Otero
- & Inmaculada Martín-Burriel
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| Open AccessA Bioluminescent Cell Assay to Quantify Prion Protein Dimerization
- Katharina Annick Wüsten
- , Pasham Parameshwar Reddy
- & Gültekin Tamgüney
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| Open AccessStructural basis for the complete resistance of the human prion protein mutant G127V to prion disease
- Zhen Zheng
- , Meilan Zhang
- & Donghai Lin
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| Open AccessGlycosylation Significantly Inhibits the Aggregation of Human Prion Protein and Decreases Its Cytotoxicity
- Chuan-Wei Yi
- , Li-Qiang Wang
- & Yi Liang
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| Open AccessInflammatory response of microglia to prions is controlled by sialylation of PrPSc
- Saurabh Srivastava
- , Elizaveta Katorcha
- & Ilia V. Baskakov
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| Open AccessLow doses of bioherbicide favour prion aggregation and propagation in vivo
- Pierre-André Lafon
- , Thibaut Imberdis
- & Véronique Perrier
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| Open AccessHigh diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions
- Alessia Franceschini
- , Simone Baiardi
- & Piero Parchi
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| Open AccessPrion strains depend on different endocytic routes for productive infection
- Andrea Fehlinger
- , Hanna Wolf
- & Ina M. Vorberg
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| Open AccessClinical Features and Sleep Analysis of Chinese Patients with Fatal Familial Insomnia
- Liyong Wu
- , Hui Lu
- & Shuqin Zhan
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| Open AccessDetection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia
- Veronica Redaelli
- , Edoardo Bistaffa
- & Fabio Moda
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| Open AccessPost-translational modifications in PrP expand the conformational diversity of prions in vivo
- Patricia Aguilar-Calvo
- , Xiangzhu Xiao
- & Christina J. Sigurdson
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| Open AccessNovel strain properties distinguishing sporadic prion diseases sharing prion protein genotype and prion type
- Laura Cracco
- , Silvio Notari
- & Pierluigi Gambetti
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| Open AccessNeurofilaments in blood and CSF for diagnosis and prediction of onset in Creutzfeldt-Jakob disease
- Petra Steinacker
- , Kaj Blennow
- & Markus Otto
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| Open AccessThe prion protein family member Shadoo induces spontaneous ionic currents in cultured cells
- Antal Nyeste
- , Claudia Stincardini
- & Ervin Welker
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| Open AccessPrions efficiently cross the intestinal barrier after oral administration: Study of the bioavailability, and cellular and tissue distribution in vivo
- Akihiko Urayama
- , Luis Concha-Marambio
- & Claudio Soto
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| Open AccessApplication of an in vitro-amplification assay as a novel pre-screening test for compounds inhibiting the aggregation of prion protein scrapie
- Matthias Schmitz
- , Maria Cramm
- & Inga Zerr
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| Open AccessPrion infection impairs lysosomal degradation capacity by interfering with rab7 membrane attachment in neuronal cells
- Su Yeon Shim
- , Srinivasarao Karri
- & Sabine Gilch
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| Open AccessGerstmann-Sträussler-Scheinker disease subtypes efficiently transmit in bank voles as genuine prion diseases
- Laura Pirisinu
- , Michele A. Di Bari
- & Romolo Nonno
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| Open AccessCharacterisation of radioiodinated flavonoid derivatives for SPECT imaging of cerebral prion deposits
- Takeshi Fuchigami
- , Yuki Yamashita
- & Morio Nakayama
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| Open AccessPreclinical detection of infectivity and disease-specific PrP in blood throughout the incubation period of prion disease
- Elizabeth B. Sawyer
- , Julie Ann Edgeworth
- & Graham S. Jackson
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| Open AccessThe non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion
- Gabriele Giachin
- , Phuong Thao Mai
- & Giuseppe Legname
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| Open AccessTheme and variations: evolutionary diversification of the HET-s functional amyloid motif
- Asen Daskalov
- , Witold Dyrka
- & Sven J. Saupe
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| Open AccessTransmission of scrapie prions to primate after an extended silent incubation period
- Emmanuel E. Comoy
- , Jacqueline Mikol
- & Jean-Philippe Deslys