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| Open AccessMechanism of cystogenesis by Cd79a-driven, conditional mTOR activation in developing mouse nephrons
- Linh Tran Nguyen Truc
- , Satoshi Matsuda
- & Hiroyasu Tsukaguchi
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| Open AccessMultiomics analysis reveals that hepatocyte nuclear factor 1β regulates axon guidance genes in the developing mouse kidney
- Annie Shao
- , Micah D. Gearhart
- & Peter Igarashi
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| Open AccessEarly childhood height-adjusted total kidney volume as a risk marker of kidney survival in ARPKD
- Kathrin Burgmaier
- , Samuel Kilian
- & Hulya Nalcacioglu
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| Open AccessCystin genetic variants cause autosomal recessive polycystic kidney disease associated with altered Myc expression
- Chaozhe Yang
- , Naoe Harafuji
- & Lisa M. Guay-Woodford
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| Open AccessRenal denervation does not affect hypertension or the renin-angiotensin system in a rodent model of juvenile-onset polycystic kidney disease: clinical implications
- Sheran Li
- , Cara M. Hildreth
- & Jacqueline K. Phillips
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| Open AccessCyst formation in proximal renal tubules caused by dysfunction of the microtubule minus-end regulator CAMSAP3
- Yuto Mitsuhata
- , Takaya Abe
- & Masamitsu Sato
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| Open AccessCollecting duct cells show differential retinoic acid responses to acute versus chronic kidney injury stimuli
- Alexandros Papadimitriou
- , Paola Romagnani
- & Qihe Xu
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| Open AccessSevere neurological outcomes after very early bilateral nephrectomies in patients with autosomal recessive polycystic kidney disease (ARPKD)
- Kathrin Burgmaier
- , Gema Ariceta
- & Hulya Nalcacioglu
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| Open AccessImplications of early diagnosis of autosomal dominant polycystic kidney disease: A post hoc analysis of the TEMPO 3:4 trial
- Peter Janssens
- , François Jouret
- & Djalila Mekahli
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| Open AccessA high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells
- Rosita R. Asawa
- , Carina Danchik
- & Natalia J. Martinez
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Article
| Open AccessPrognosis of Vascular Access in Haemodialysis Patients with Autosomal Dominant Polycystic Kidney Disease
- Tsung-Lun Lee
- , Chun-Fan Chen
- & Chih-Ching Lin
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| Open AccessRenal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective
- Anish A. Kanhai
- , Hester Bange
- & Wouter N. Leonhard
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| Open AccessIdentification of housekeeping genes for microRNA expression analysis in kidney tissues of Pkd1 deficient mouse models
- J. J. Muñoz
- , A. C. Anauate
- & I. P. Heilberg
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| Open AccessA high throughput zebrafish chemical screen reveals ALK5 and non-canonical androgen signalling as modulators of the pkd2−/− phenotype
- A. Metzner
- , J. D. Griffiths
- & A. C. M. Ong
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| Open AccessGenetic Characteristics of Korean Patients with Autosomal Dominant Polycystic Kidney Disease by Targeted Exome Sequencing
- Hyunsuk Kim
- , Hayne Cho Park
- & Curie Ahn
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Article
| Open AccessPolycystin-1 Regulates Actomyosin Contraction and the Cellular Response to Extracellular Stiffness
- Elisa Agnese Nigro
- , Gianfranco Distefano
- & Alessandra Boletta
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Article
| Open AccessPrognostic Performance of Kidney Volume Measurement for Polycystic Kidney Disease: A Comparative Study of Ellipsoid vs. Manual Segmentation
- Beili Shi
- , Pedram Akbari
- & York Pei
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| Open AccessClinical courses and complications of young adults with Autosomal Recessive Polycystic Kidney Disease (ARPKD)
- Kathrin Burgmaier
- , Samuel Kilian
- & Max C. Liebau
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| Open AccessRenal expression of JAK2 is high in polycystic kidney disease and its inhibition reduces cystogenesis
- Foteini Patera
- , Alex Cudzich-Madry
- & Maria Fragiadaki
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| Open AccessPKD1 Duplicated regions limit clinical Utility of Whole Exome Sequencing for Genetic Diagnosis of Autosomal Dominant Polycystic Kidney Disease
- Hamad Ali
- , Fahd Al-Mulla
- & Peter C. Harris
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| Open AccessMetabolic Phenotyping of Anks3 Depletion in mIMCD-3 cells - a Putative Nephronophthisis Candidate
- Manuel Schlimpert
- , Simon Lagies
- & Bernd Kammerer
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Article
| Open AccessActivation of Calcium-Sensing Receptor increases intracellular calcium and decreases cAMP and mTOR in PKD1 deficient cells
- Annarita Di Mise
- , Grazia Tamma
- & Giovanna Valenti
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| Open AccessInhibition of Hedgehog signaling suppresses proliferation and microcyst formation of human Autosomal Dominant Polycystic Kidney Disease cells
- Luciane M. Silva
- , Damon T. Jacobs
- & Pamela V. Tran
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| Open AccessA cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed
- Cheng-Chao Lin
- , Mahiro Kurashige
- & Gregory G. Germino
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| Open AccessNEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology
- Jun-ya Kaimori
- , Cheng-Chao Lin
- & Gregory G. Germino
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| Open AccessMetformin Inhibits Cyst Formation in a Zebrafish Model of Polycystin-2 Deficiency
- Ming-Yang Chang
- , Tsu-Lin Ma
- & Yi-Chuan Cheng
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| Open AccessThe centrosomal OFD1 protein interacts with the translation machinery and regulates the synthesis of specific targets
- Daniela Iaconis
- , Maria Monti
- & Brunella Franco
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| Open AccessSix2creFrs2α knockout mice are a novel model of renal cystogenesis
- Pawan Puri
- , Daniel Bushnell
- & Carlton M. Bates
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| Open AccessSystem analysis of gene mutations and clinical phenotype in Chinese patients with autosomal-dominant polycystic kidney disease
- Meiling Jin
- , Yuansheng Xie
- & Xiangmei Chen
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| Open AccessDeciphering Variability of PKD1 and PKD2 in an Italian Cohort of 643 Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD)
- Paola Carrera
- , Silvia Calzavara
- & Maurizio Ferrari
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| Open AccessIdentification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models
- Tomonaga Ameku
- , Daisuke Taura
- & Kenji Osafune